Detail of "68-05-3"

Reference

Heat-resistant electric insulators

Heat-resistant electric insulators. (Mitsubishi Electric Corp., Japan). Jpn. Tokkyo Koho JP 58021813 B4 4 May 1983 Showa, 6 pp. (Japanese). (Japan). CODEN: JAXXAD. CLASS: IC: H01F041-12; H01B003-54; H01F005-06; H02K015-12. APPLICATION: JP 76-89785 27 Jul 1976. DOCUMENT TYPE: Patent CA Section: 37 (Plastics Manufacture and Processing) A substrate was treated with a mixt. of methylated melamine-phenoxy resin reaction product, polyisocyanate, and quaternary ammonium salt, wound on an elec. conductor, impregnated with an epoxy resin, and cured to give heat-resistant elec. insulation. Thus, a phenoxy resin 100, 6:4 MEK-BuOH 100, and methylolmelamine 30 parts were heated at 130° for 3 h, mixed with an epoxy resin hardener (MDI [101-68-8] 100, Et4N+ I- [68-05-3] 1, and MEK 100 parts), and coated on a reconstituted mica-glass tape. The coated tape was wound on an elec. conductor, impregnated with Epikote 828 [25068-38-6] in vacuo, and heated at 150° for 8 h and 200° for 5 h to give insulation with tan d 0.3, o.4, and 0.7 after 0 and 16 days at 200° and 16 days at 250°, resp.

Autoradiographic studies on the distribution of quaternary ammonium compounds IV

Autoradiographic studies on the distribution of quaternary ammonium compounds IV. Adsorption of bisonium ions to rat tissues as revealed by in vitro whole-body adsorption autoradiography. Shindo, Hideyo; Nakajima, Eiichi; Shigehara, Eiji (Cent. Res. Lab., Sankyo Co., Ltd., Tokyo, Japan).Chemicals with cas numbers 541-22-0 and 61467-38-7 also play role. Chem. Pharm. Bull., 24(10), 2327-34 (English) 1976. CODEN: CPBTAL. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) A technique which was designated as ''whole-body adsorption autoradiog.'' was applied to find binding characteristics of bis- and mono-quaternary ammonium ions by rat various tissues. Rat freeze-dried whole-body sections were incubated in an aq. soln. of 14C-labeled deca- [541-22-0], hexa- [60-25-3], and dimethonium diiodide [10428-58-7] and tetraethyl- [68-05-3] and cetyltrimethylammonium [6899-10-1]. After rinsing and being freeze-dried, the adsorption of radioactivity was detected by autoradiog. It was found that bisonium ions are highly adsorbed in the cartilage tissues of vertebra, sternum and trachea, wherein a similar high accumulation occurs in vivo, and appreciably adsorbed in the thymus, salivary gland and bone marrow. These adsorptions were interpreted as being due to an ionic bonding of the bis-quaternary ammonium cations to the sulfate and phosphate anions of the chondroitin sulfate [9007-28-7] and cellular DNA, resp., probably by forming a bridged structure, with an aid of Alcian Blue staining of the rat whole-body sections (whole-body histochem.). Close relations between the in vitro adsorption characteristics and the in vivo distribution patterns are discussed. It appears that a physicochem. binding of a drug mol. to the tissue macromols. plays an important role in detg. the in vivo distribution pattern in animal body and that a combined use of this method with conventional whole-body autoradiog. provides a useful tool in establishing the drug distribution characteristics and their interpretation. .