Reference

Synthesis of polyimide-poly(arylene ether sulfone) copolymers

Synthesis of polyimide-poly(arylene ether sulfone) copolymers. Johnson, Bruce C.; McGrath, J. E. (Dep. Chem. Polym. Mater., Virginia Tech, Blacksburg, VA 24061, USA). Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.), 25(2), 49-51 (English) 1984. CODEN: ACPPAY. ISSN: 0032-3934. DOCUMENT TYPE: Journal CA Section: 35 (Chemistry of Synthetic High Polymers) High-mol.-wt. tractable arom. polyether-polyimide-polysulfone [91858-47-8] samples contg. 5-25% N,N'-bis(4-hydroxyphenyl)benzophenonetetracarboxylic acid diimide (I) [53417-18-8] linkages were prepd. in situ via nucleophilic arom. substitution of I with 4,4'-dihydroxybiphenyl and bis(4-chlorophenyl) sulfone using a N-cyclohexyl-2-pyrrolidone (II) [6837-24-7]-N-methylpyrrolidone (III) [872-50-4] () solvent system and anhyd. K2CO3. Copolymers synthesized with >25% I did not reach high mol. wts. as indicated by their low intrinsic viscosities and inability to form films. III was the reaction and polymer solvent while II served as a dehydrating agent. Intrinsic viscosity of the products decreased from 0.59 to 0.40 cP as II concn. decreased from 50 to 10°.

Teratogenesis study of N-cyclohexyl-2-pyrrolidone in rats and rabbits

Teratogenesis study of N-cyclohexyl-2-pyrrolidone in rats and rabbits. Becci, Peter J.; Reagan, Elizabeth L.; Wedig, John H.; Barbee, Steven J. (Food and Drug Res. Lab., Inc., Waverly, NY 14892, USA). Fundam. Appl. Toxicol., 4(4), 587-93 (English) 1984. CODEN: FAATDF. ISSN: 0272-0590. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Teratogenesis studies were performed in rats and rabbits given N-cyclohexyl-2-pyrrolidone (I) [6837-24-7]. Dosages of 0, 15, 50, 150, or 500 mg/kg/day were administered by gavage to pregnant rats on days 6-15 of gestation. Dosages of 0, 10, 30, 100, or 300 mg/kg/day were administered by gavage to pregnant rabbits on days 6-18 of gestation. Animals were killed and subjected to uterine examn. on day 20 of gestation for rats and on day 29 for rabbits. There were no significant differences between the vehicle control and I-treated groups for implantation nos. or live or dead fetuses, resorptions, and fetal body wt. in rats and rabbits. Dam body wt. gain during gestation was comparable among groups. External gross visual examn. of the fetus as well as examn. of skeletal and soft tissues revealed no effects related to treatment with I.