Reference

Spectrophotometric determination of sulbactam by reaction with 1,2,4-triazole

Spectrophotometric determination of sulbactam by reaction with 1,2,4-triazole. Haginaka, Jun; Wakai, Junko; Yasuda, Hiroyuki; Uno, Toyozo; Nakagawa, Terumichi (Fac. Pharm. Sci., Mukogawa Women's Univ., Nishinomiya 663, Japan). Analyst (London), 109(8), 1057-9 (English) 1984. CODEN: ANALAO. ISSN: 0003-2654. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Sulbactam [68373-14-8] was detd. by a simple and rapid spectrophotometric assay method based on the reaction with 2M 1,2,4-triazole [288-88-0] in soln. (pH 10.0) for 15 min at 50° followed by measurement of UV absorbance at 326 nm of the reaction product. The method is quant. for sulbactam concns. ￡0.2 mg/mL, and specific to intact sulbactam without interference of penicillins, cephalosporins, and degrdn. products. 68373-14-8 which is the cas registry number of one of substances is just one of reagents here. .

Reproduction studies with sulbactam and combinations of sulbactam and cefoperazone in rats

Reproduction studies with sulbactam and combinations of sulbactam and cefoperazone in rats. Horimoto, Masao; Sakai, Takeo; Ohtsuki, Isao; Noguchi, Yasuhiro (New Product Res. Cent., Pfizer Taito, Co., Ltd., Nagoya, Japan). Chemotherapy (Tokyo), 32(Suppl. 4), 108-15 (Japanese) 1984. CODEN: NKRZAZ. ISSN: 0369-4682. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Neither sulbactam [68373-14-8] alone nor the sulbactam-cefoperazone mixt. [92739-15-6] appeared to have any toxic effects on reprodn. in rats, with the exception of a slight decrease in survival rate of offspring of rats treated during pregnancy with high doses of the drugs. No teratogenic effects were obsd.