Detail of "6856-31-1"

CAS Number:
6856-31-1
Name:
1-(3-Hydroxy-1,1-diphenylpropyl)piperidinium methanesulphonate
Molecular Structure:
Formula:
C₂₁H₂₉NO₄S
Molecular Weight:
391.5243
Synonyms:
Pridinol mesilate;1-Piperidinepropanol,R,R-diphenyl-,methanesulfonate (salt);Lyseen;1,1-diphenyl-3-(1-piperidyl)propan-1-ol; methanesulfonic acid;Pridinol mesilate (JAN);511-45-5;Pridinol methanesulfonate;Pridinol methanesulfonate salt;Konlax (TN);
EINECS:
229-953-2
Melting Point:
152.5-155 °C
Boiling Point:
585.1 °C at 760 mmHg
Flash Point:
307.6 °C
Solubility:
Freely soluble in Chloroform; soluble in methanol; practically insoluble in toluene and in ether.
Appearance:
White to Off-White Crystalline Powder
Hazard Symbols:
Xn
Risk Codes:
20/21/22
Safety:
36 Details

Display：

white to white off powder assy:98%

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Studies on the elution rate of marketed tablets: Studies on the elution rate of marketed tablets. II. Shibata, Kazuo (2nd Tokyo Natl. Hosp., Tokyo, Japan). Iryo, 31(5), 444-9 (Japanese) 1977. CODEN: IRYOAV. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Different brand names of sugar- or film-coated tablets having the same active ingredients (metoclopramide [364-62-5], benzidamine-HCl [132-69-4], pridinol mesylate [6856-31-1], promethazine-HCL [58-33-3], dicyclomine-HCl [67-92-5], butylscopolamine bromide [149-64-4], glutathione [70-18-8], meclophenoxate-HCl [3685-84-5] and buformin-HCl [15537-73-2]) were checked for their disintegrating time, dissoln. and active ingredient contents. The results were variable. Some products had higher dissoln. and disintegrating time than others.

Topical preparations of pridinol mesylate containing glycerin and benzyl alcohol: Topical preparations of pridinol mesylate containing glycerin and benzyl alcohol. Oomura, Hisako; Wada, Yoshio; Yamada, Yoshiharu; Mizuno, Keizo ( Mikasa Seiyaku Kk, Japan). Jpn. Kokai Tokkyo Koho JP 08325149 A2 10 Dec 1996 Heisei, 7 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: ICM: A61K031-445. ICS: A61K009-06; A61K009-08; A61K009-70; A61K047-10. APPLICATION: JP 1995-182035 26 May 1995. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) The topical prepns. comprise pridinol mesylate (I) as a muscle relaxant, glycerin, PhCH2OH, and bases. The prepns. in the forms of adhesive patches are also claimed. A polyester film was coated with a compn. contg. a water-sol. polymer 8.0, a crosslinking agent 0.31, a filler 0.25, methylparaben 0.1, propylparaben 0.05, glycerin 25.0, PhCH2OH 5.0, a surfactant 1.0, I 1.Several substances with their cas registry numbers 6856-31-1 and 100-51-6 may be metioned in this study.0, Na edetate 0.25, a pH controller 0.6, and H2O 57.44 wt.% to give an adhesive prepn. AUC of I upon applying the adhesive prepn. onto a shaven part of the back of a guinea pig was 1258.8 ng-h/mL, vs. 742.9 ng-h/mL for a control prepn. contg. H2O 55.45, tartaric acid 0.9, I 1, glycerin 30, light SiO2 2, a water-sol. polymer 7, a crosslinking agent 0.2, a surfactant 0.6, mint oil 1 wt.%, and diisopropanolamine. .