Detail of "6899-04-3"

Reference

L-Glutamine D-fructose-6-P aminotransferase regulation by glucose-6-P and UDP-N-acetylglucosamine

L-Glutamine D-fructose-6-P aminotransferase regulation by glucose-6-P and UDP-N-acetylglucosamine. Tourian, A.; Callahan, M.; Hung, W. (Dep. 56-73-5 and 9030-45-9 are also occured in this study. Med., Duke Univ., Durham, NC 27710, USA). Neurochem. Res., 8(12), 1589-95 (English) 1983. CODEN: NEREDZ. ISSN: 0364-3190. DOCUMENT TYPE: Journal CA Section: 13 (Mammalian Biochemistry) L-Glutamine D-fructose-6-phosphate aminotransferase (EC 5.3.1.19) regulates hexosamine synthesis. An affinity purified human fibroblast aminotransferase and specific radioisotope assays were used to show an independent inhibition of the aminotransferase by glucose 6-phosphate (glucose-6-P). Addnl., at concn. of UDP-N-acetylglucosamine and glucose-6-P where either sugar has no independent inhibitory effect, there is an allosteric and significant inhibition of the aminotransferase. .

Glutamine production in high concentrations with energy transfer employing glutamine synthetase from Micrococcus glutamicus

Glutamine production in high concentrations with energy transfer employing glutamine synthetase from Micrococcus glutamicus. Tachiki, Takashi; Suzuki, Hideyuki; Wakisaka, Shinji; Yano, Toshihiro; Tochikura, Tatsurokuro (Dep. Food Sci. Technol., Kyoto Univ., Kyoto, Japan). J. Gen. Appl. Microbiol., 29(5), 355-63 (English) 1983. CODEN: JGAMA9.There are some reagents with their cas registry numbers 9023-70-5 and 56-85-9 are used in this study. ISSN: 0022-1260. DOCUMENT TYPE: Journal CA Section: 16 (Fermentation and Bioindustrial Chemistry) Glutamine [56-85-9] was produced by coupling the glutamine synthetase [9023-70-5] from M. glutamicus with sugar fermn. of bakers' yeast as an energy-generating system. With 429 units/mL of glutamine synthetase and 40 mg/mL of yeast cells, 120 mM of glutamate [56-86-0] was converted completely to glutamine in 3-4 h, and 160-170 mM of glutamine was formed in 5 h from 350 mM of the substrates glutamate and NH4Cl, with a yield of ~40%, based on the energy released by the yeast during sugar fermn. The activity ratio of sugar fermn. and glutamine synthetase was again confirmed to be important for achievement of energy-coupling in systems with high concns. of glutamate and NH4Cl. Glutamine formation was partially stimulated by the addn. of Mg2+ in concns. at which yeast fermn. of sugar showed no response to the cation, but was greatly stimulated by the addn. of a small amt. of Co2+. This same Co2+ effect was also obsd. in the reaction with cell-free exts. or toluol-treated cells of M. glutamicus. .