Detail of "69002-84-2"

CAS Number:
69002-84-2
Name:
5-Hydroxydiclofenac
Molecular Structure:
Formula:
C₁₄H₁₁Cl₂NO₃
Molecular Weight:
312.15
Synonyms:
Benzeneacetic acid,2-[(2,6-dichlorophenyl)amino]-5-hydroxy-;2-[2-(2,6-dichloroanilino)-5-hydroxyphenyl]acetic acid;(2-(2,6-Dichloroanilino)-5-hydroxyphenyl)acetic acid;Acetic acid, (2-(2,6-dichloroanilino)-5-hydroxyphenyl)-;
Density:
1.52 g/cm³
Boiling Point:
444.8 °C at 760 mmHg
Flash Point:
222.8 °C

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High-performance liquid chromatographic determination of diclofenac and its monohydroxylated metabolites in biological fluids: High-performance liquid chromatographic determination of diclofenac and its monohydroxylated metabolites in biological fluids. Godbillon, J.; Gauron, S.; Metayer, J. P. (Biopharm. Res. Cent., Ciba-Geigy, Rueil-Malmaison 92506, Fr.). J. Chromatogr., 338(1), 151-9 (English) 1985. CODEN: JOCRAM. ISSN: 0021-9673. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Sensitive and selective HPLC assays for diclofenac [15307-86-5] and its monohydroxylated metabolites in biol. fluids are described. Using UV detection at 282 nm, diclofenac is assayed in plasma at 310 ng/mL; total (free + conjugated) diclofenac and its monohydroxylated metabolites (the sum of 3- [69002-85-3] plus 4'-hydroxydiclofenac [64118-84-9] and 5-hydroxydiclofenac [69002-84-2]) are assayed in urine after chem. hydrolysis at concns. 3200 ng/mL.