Reference

Syntheses of highly functionalized d,g-unsaturated-a-amino acids

All Rights Reserved. Syntheses of highly functionalized d,g-unsaturated-a-amino acids. Chen, Siyuan; Williams, Robert M. (Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA). Tetrahedron, 62(50), 11572-11579 (English) 2006 Elsevier Ltd. CODEN: TETRAB. ISSN: 0040-4020. DOCUMENT TYPE: Journal CA Section: 34 (Amino Acids, Peptides, and Proteins) Section cross-reference(s): 27 The synthesis of several g,d-unsatd.-a-amino acid derivs. I (Boc = tert-butoxycarbonyl; R1 = 2-Br-C6H4, 2-NO2-C6H4, 3-CN-C6H4, 3-thiophenyl, etc, R2 = H; or R1 = H, R2 = 4-MeO-C6H4, 3-CN-C6H4, 3-thiophenyl, etc.There are some commonly used reagents with their cas registry numbers 69113-59-3 and 609-73-4 in this article.) is described. The method features regioselective stannylation of propargylglycine derivs. followed by Stille coupling reactions. .