Reference

N1-Phthalidyl-5-fluorouracil

N1-Phthalidyl-5-fluorouracil. (Grelan Pharmaceutical Co., Ltd., Japan). Jpn. Kokai Tokkyo Koho JP 58140087 A2 19 Aug 1983 Showa, 3 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: IC: C07D405-04. ICA: A61K031-505. ICI: C07D405-04, C07D239-00, C07D307-00. APPLICATION: JP 82-21995 16 Feb 1982. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Anticarcinogenic (no data) N1-phthalidyl-5-fluorouracil (I) was prepd. by reaction of 5-fluorouracil (II) with III (X = halo) in the presence of inorg. carbonates. 6940-49-4 and 51-21-8 which are cas registry numbers of chemicals are mentioned. Thus, 27.6 g K2CO3 was added to a mixt. of 52 g II and 35.2 g III (X = Br) in DMF over 30 min at room temp. to give, after 1.5 h, 82% I. .

Photochemical behavior of indane-1,2,3-trione in degassed alcoholic solutions: formation of 3-substituted phthalides

Photochemical behavior of indane-1,2,3-trione in degassed alcoholic solutions: formation of 3-substituted phthalides. Tatsugi, Jiro; Hara, Tomoaki; Izawa, Yasuji (Dep. Applied Chem., Aichi Inst. Technol., Toyota 470-03, Japan).There are some reagents with their cas registry numbers 6940-49-4 and 187969-54-6 are used in this study. Chemistry Letters, (2), 177-178 (English) 1997 Nippon Kagakkai. CODEN: CMLTAG. ISSN: 0366-7022. DOCUMENT TYPE: Journal CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Irradn. of indane-1,2,3-trione in degassed alc. solns. affords 3-(alkoxycarbonyl)phthalides I (R = CO2R1, R1 = ME, Et, CHMe2) as the major product together with 3-alkoxyphthalides I (R = OMe, OEt, OCHMe2). 3-(Alkoxycarbonyl)phthalides may be derived from the reaction between alcs. and the spirooxiranone intermediate, generated photochem. by cleavage of the bond between two carbonyl groups of indane-1,2,3-trione via a cyclobutenone biradical deriv. .