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CAS No.: | 70-69-9 |
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Name: | 4'-AMINOPROPIOPHENONE |
Article Data: | 24 |
Molecular Structure: | |
Formula: | C9H11 N O |
Molecular Weight: | 149.192 |
Synonyms: | Propiophenone,4'-amino- (6CI,8CI); 1-(4-Aminophenyl)-1-propanone; 4-Propanoylaniline;4-Propionylaniline; 4'-Aminopropiophenone; NSC 3187; NSC 404994; PAPP;p-Aminopropiophenone |
Density: | 1.067g/cm3 |
Melting Point: | 135-140 °C |
Boiling Point: | 305.8oC at 760 mmHg |
Flash Point: | 138.7oC |
Solubility: | 352.1mg/L(37.5 oC) |
Appearance: | yellow-brown crystalline powder, scales |
Hazard Symbols: | T |
Risk Codes: | R25 |
Safety: | Poison by ingestion and intraperitoneal routes. Ingestion of large doses can cause cyanosis. A flammable liquid. When heated to decomposition it emits toxic fumes of NOx. |
PSA: | 43.09000 |
LogP: | 2.44270 |
IUPAC Name: 1-(4-Aminophenyl)propan-1-one
Synonyms of p-Aminopropiophenone (CAS NO.70-69-9) : 1-(4-Aminophenyl)propan-1-one ;1-Propanone, 1- (4-aminophenyl)- ; 1-Propanone, 1-(4-aminophenyl)- ; 4-Aminopropiophenone
Product Categories: Aromatic Propiophenones (substituted)
CAS NO: 70-69-9
Molecular Formula:C9H11NO
Molecular Weight :149.1897
Molecular Structure :
EINECS:200-742-7
Index of Refraction:1.559
Surface Tension: 43 dyne/cm
Density: 1.067 g/cm3
Flash Point: 138.7 °C
Enthalpy of Vaporization: 54.62 kJ/mol
Boiling Point: 305.8 °C at 760 mmHg
Vapour Pressure: 0.000805 mmHg at 25°C
Melting Point: 135-140 °C
Appearance: p-Aminopropiophenone (CAS NO.70-69-9) is yellow-brown crystalline powder, scales.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
bird - wild | LD50 | oral | 133mg/kg (133mg/kg) | Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983. | |
cat | LD50 | oral | 5600ug/kg (5.6mg/kg) | GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | Bulletin of Environmental Contamination and Toxicology. Vol. 30, Pg. 122, 1983. |
dog | LD50 | intravenous | 7150ug/kg (7.15mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 109, 1947. | |
dog | LD50 | oral | 50mg/kg (50mg/kg) | BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN | Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 31, 1944. |
dog | LD50 | unreported | 7500ug/kg (7.5mg/kg) | Canadian Journal of Biochemistry and Physiology. Vol. 38, Pg. 667, 1960. | |
guinea pig | LD50 | oral | 1020mg/kg (1020mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Toxicology Letters. Vol. 23, Pg. 359, 1984. |
mammal (species unspecified) | LD50 | oral | 5600ug/kg (5.6mg/kg) | Bulletin of Environmental Contamination and Toxicology. Vol. 30, Pg. 122, 1983. | |
mouse | LD50 | intraperitoneal | 80mg/kg (80mg/kg) | National Technical Information Service. Vol. AD277-689, | |
mouse | LD50 | intravenous | 145mg/kg (145mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Toxicology Letters. Vol. 23, Pg. 359, 1984. |
mouse | LD50 | oral | 168mg/kg (168mg/kg) | General Pharmacology. Vol. 14, Pg. 465, 1983. | |
quail | LD50 | oral | > 316mg/kg (316mg/kg) | Ecotoxicology and Environmental Safety. Vol. 6, Pg. 149, 1982. | |
rabbit | LD50 | intramuscular | 9600ug/kg (9.6mg/kg) | Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. Vol. 9, Pg. 178, 1988. | |
rat | LD50 | intraperitoneal | 55mg/kg (55mg/kg) | BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN | Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 31, 1944. |
rat | LD50 | oral | 177mg/kg (177mg/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING | Bulletin of Environmental Contamination and Toxicology. Vol. 30, Pg. 122, 1983. |
Reported in EPA TSCA Inventory. EPA Extremely Hazardous Substances List.
Poison by ingestion and intraperitoneal routes. Ingestion of large doses can cause cyanosis. A flammable liquid. When p-Aminopropiophenone (CAS NO.70-69-9) is heated to decomposition, it emits toxic fumes of NOx.
Hazard Codes T
Risk Statements 25
R25 :Toxic if swallowed.
Safety Statements 45-28
S28:After contact with skin, wash immediately with plenty of soap-suds.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR 2811
HazardClass 6.1(b)
PackingGroup III
DOT Classification: 3; Label: Flammable Liquid