Detail of "71299-82-6"

CAS Number:
71299-82-6
Name:
beta-Cyclodextrin, compd. with 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid
Molecular Weight:
0
Synonyms:
chinoin 137

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Investigation of indomethacin/b-cyclodextrin and indomethacin/hydroxypropyl b-cyclodextrin inclusion complexes, NMR contribution to prove the inclusion: Investigation of indomethacin/b-cyclodextrin and indomethacin/hydroxypropyl b-cyclodextrin inclusion complexes, NMR contribution to prove the inclusion. Wouessidjewe, D.; Lin, S. Z.; Djedaini, F.; Perly, B. 71299-82-6 and 134451-29-9 are also occured in this study.; Duchene, D. (Fac. Pharm., Univ. Paris-Sud, Chatenay Malabry 92292, Fr.). Minutes Int. Symp. Cyclodextrins, 5th, 332-8. Edited by: Duchene, Dominique. Ed. Sante: Paris, Fr. (English) 1990. CODEN: 57LSAJ. DOCUMENT TYPE: Conference CA Section: 33 (Carbohydrates) A symposium on the interaction of indomethacin and sodium indomethacin with both b-cyclodextrin and hydroxypropyl-b-cyclodextrin. The characterization of solid state materials, using DSC anal., indicated the possible existence of complexes. Meanwhile, NMR proton studies, performed at very high magnetic field, allowed to prove the 1/1 inclusion compd. in the case of sodium indomethacin; and clearly showed that indomethacin (acid) does not become included in cyclodextrins in aq. media. The assocn. const. derived from the Benesi-Hildebrand method was calcd. for the sodium indomethacin/b-cyclodextrin complex and was found relatively low. .