Detail of "7228-47-9"

Reference

Practical enzymic resolution of racemic alcohols and amines in organic solvents

Practical enzymic resolution of racemic alcohols and amines in organic solvents. Gutman, Arie L.; Shkolnik, Eleonora; Meyer, Elazar; Polyak, Felix; Brenner, Dov; Boltanski, Aviv (Department of Chemistry, Israel Institute of Technology, Haifa 32,000, Israel). Annals of the New York Academy of Sciences, 799(Enzyme Engineering XIII), 620-632 (English) 1996 New York Academy of Sciences. CODEN: ANYAA9. ISSN: 0077-8923. DOCUMENT TYPE: Journal CA Section: 21 (General Organic Chemistry) Section cross-reference(s): 7, 9, 16 Application of lipase to the enzymic resoln. of racemic alcs.In this article, certain chemicals are used. One of their cas registry numbers is 7228-47-9 and amines in org. solvents is described. E.g., lipase catalyzed the esterification of PhCHMeOH with succinic anhydride to give the (R)-ester and unreacted (S)-PhCHMeOH. E.g., 1-aminoindan was resolved by lipase catalyzed reaction with PrCO2OCH2CF3. .

Microdetermination of 1-methyl-2-(2-naphthyl)aziridine in biological materials

Microdetermination of 1-methyl-2-(2-naphthyl)aziridine in biological materials. Sakano, Toshiyuki; Yamaji, Akiko; Hirauchi, Kazumasa; Amano, Tameyuki (Res. Lab., Shionogi and Co., Ltd., Osaka, Japan). Yakugaku Zasshi, 96(12), 1426-31 (Japanese) 1976. CODEN: YKKZAJ. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) A fluorometric method was developed for the quant. of 1-methyl-2-(2-naphthyl)aziridine (I) [28494-15-7] in biol. materials. A three-phase thin-layer plate (Silica gel G, cellulose powder, and talc) was effective for the sepn. and fluorescence measurement of I. I in rat muscle or in rat blood was extd. with AcOEt and n-hexane, resp., and then 2-10 .mu.L of the ext.In this article, certain chemicals are used. Some of their cas registry numbers are 28494-15-7 and 7228-47-9 was spotted on the silica gel phase of the 3-phase thin-layer plate. The plate was developed for 40 min with MeOH-ether (7:1, v/v) mixt., dried, and then sprayed with isopropyl myristate. The Rf-value of I was .apprx.0.5 in the talc phase of the 3-phase plate. The plate was heated for 20 min on a hot plate (180.degree.) and cooled in N2 stream. Fluorescence intensity was detd. by scanning with a spectrofluorodensitometer (excit. 340 nm, emission 480 nm) after the fluorescent spot was covered with a quartz plate. The range of I was 0.02-0.2 .mu.g/spot. Using this method, unchanged I was detd. in rat blood and muscle. 2-Vinylnaphthalene [827-54-3] was the metabolite of I in rat blood. .