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7250-67-1

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CAS Number:
7250-67-1
Name:
Pyrrolidine,1-(2-chloroethyl)-, hydrochloride (1:1)
Superlist Name:
N-(2-Chloroethyl)pyrrolidine hydrochloride
Molecular Structure:
Formula:
C₆H₁₂ClN·HCl
Molecular Weight:
170.08
Synonyms:
Pyrrolidine,1-(2-chloroethyl)-, hydrochloride (6CI,7CI,8CI,9CI);1-(2-Chloroethyl)pyrrolidine hydrochloride;1-(2-Chloroethyl)pyrrolidinium chloride;2-(1-Pyrrolidino)ethyl chloride hydrochloride;2-(1-Pyrrolidinyl)ethyl chloridehydrochloride;2-Pyrrolidinoethyl chloride hydrochloride;2-Pyrrolidinyl-1-chloroethanehydrochloride;N-(b-Chloroethyl)pyrrolidine hydrochloride;Pyrrolidinoethyl chloride hydrochloride;b-Pyrrolidinoethyl chloride hydrochloride;
EINECS:
230-660-7
Melting Point:
167-170 °C(lit.)
Boiling Point:
170.5 °C at 760 mmHg
Flash Point:
56.9 °C
Solubility:
Soluble in water, chloroform, methanol, ethanol; slightly soluble in acetone, ethyl ether; insoluble in ethyl acetate, benzene
Appearance:
white to off-white crystals or crystalline powder
Hazard Symbols:
Xn,Xi
Risk Codes:
36/37/38-20/22
Safety:
26-36-37/39 Details
particular:
particular

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Reference

Studies in antifertility agents: Studies in antifertility agents. Part XXXIX. Synthesis of pyrrolidinoethyl ethers of triphenylcyclohexenes. Prasad, Mohan; Rastogi, Shri Nivas (Div. Med. Chem.Chemicals with cas numbers 88362-86-1 and 7250-67-1 also play role., Cent. Drug Res. Inst., Lucknow 226 001, India). Indian J. Chem., Sect. B, 22B(7), 669-72 (English) 1983. CODEN: IJSBDB. ISSN: 0376-4699. DOCUMENT TYPE: Journal CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Section cross-reference(s): 1, 25 3-(Phenyl/p-methoxyphenyl)-5-phenylcyclohexanones, prepd. by catalytic redn. of the corresponding cyclohexenones followed by chromic acid oxidn. of the resulting cyclohexanols, undergo Grignard reaction with 4-R1C6H4Br (R1 = H, MeO) to give triphenylcyclohexanols I (R = H, R1 = MeO, R = MeO, R1 = H). I were dehydrated to give cyclohexenes II - IV (R2 = MeO), which were converted to the title compds. II - IV (R2 = 2-pyrrolidinoethyoxy). None of these ethers prevents pregnancy at 10 mg/kg in female rats. .

Potential hypolipidemic agents derived from 3-hydroxy-17,17-dimethylgona-1,3,5(10),8,11,13-hexaene: Potential hypolipidemic agents derived from 3-hydroxy-17,17-dimethylgona-1,3,5(10),8,11,13-hexaene. Chinn, Leland J.; Salamon, Karlene W. (Searle Lab., Div., G. D. Searle and Co., Chicago, Ill., USA). J. Med. Chem., 20(2), 229-33 (English) 1977. CODEN: JMCMAR.Several substances with their cas registry numbers 598-72-1 and 7250-67-1 may be metioned in this study. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 32 Dehydration and rearrangement of 17.alpha.-methylestradiol 3-methyl ether [15236-73-4] with H2SO4 followed by aromatization with chloranil and demethylation gave 3-hydroxy-17,17-dimethylgona-1,3,5(10),8,11,13-hexaene (I, R = H) (II) [61237-26-1]. Eleven addnl. derivs. were prepd. by O-alkylation of II. II, I[R = Et2N(CH2)2, oxalate] [61237-33-0], I(R = pyrrolidinylethyl) [61265-81-4], I(R = CMe2CO2H) [61265-50-7], I(R = CMe2CH2OH) [61237-34-1], and I[R = CMe2CH2OC(:O)(CH2)2CO2Me] [61237-35-2], at 10 mg/kg intragastrically, significantly lowered the plasma cholesterol level of hypercholesteremic rats. II had uterotropic activity in mice, while some other derivs. were toxic or caused accumulation of desmosterol. .

7250-67-1

Pyrrolidine,1-(2-chloroethyl)-, hydrochloride (1:1)

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CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

CAS No.7250-67-1 N-(2-Chloroethyl)pyrrolidine hydrochloride

Reference