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73-09-6

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Basic Information
CAS No.: 73-09-6
Name: Etozolin
Article Data: 2
Molecular Structure:
Molecular Structure of 73-09-6 (Etozolin)
Formula: C13H20 N2 O3 S
Molecular Weight: 284.379
Synonyms: Aceticacid, [3-methyl-4-oxo-5-(1-piperidinyl)-2-thiazolidinylidene]-, ethyl ester(9CI); D2,a-Thiazolidineacetic acid,3-methyl-4-oxo-5-piperidino-, ethyl ester (7CI,8CI); (?à)-Etozolin; (?à)-Etozoline;3-Methyl-4-oxo-5-piperidino-D2,a-thiazolidineacetic acid ethylester; Elkapin; Ethyl 3-methyl-4-oxo-5-piperidino-D2,a-thiazolidineacetate; Ethyl3-methyl-4-oxo-5-piperidinothiazolidinylidene-2-acetate; Etozolin; Etozoline;Go 787; NSC 310039; W 2900A
Density: 1.288g/cm3
Melting Point: 140°
Boiling Point: 449.4°C at 760 mmHg
Flash Point: 225.6°C
Safety: Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Used as a diuretic. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also ESTERS.
PSA: 75.15000
LogP: 1.28390
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Toxicity Data With Reference

1.   

orl-rat LD50:10,250 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),1745.
2.   

ipr-rat LD50:1575 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),1745.
3.   

ivn-rat LDLo:110 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),1745.
4.   

orl-mus LD50:8670 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),1745.
5.   

ipr-mus LD50:1210 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),1745.
6.   

ivn-mus LDLo:57 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),1745.
7.   

orl-dog LDLo:3200 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),1745.

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Used as a diuretic. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also ESTERS.