Reference

Electrochemical synthesis of ketones and aldehydes

Electrochemical synthesis of ketones and aldehydes. Moingeon, Marie Odile; Chaussard, Jacques (Societe Nationale des Poudres et Explosifs, Fr.). Fr.In this study，7306-46-9 is also used. Demande FR 2579626 A1 3 Oct 1986, 15 pp. (France) CODEN: FRXXBL. CLASS: ICM: C25B003-04. APPLICATION: FR 85-4742 29 Mar 1985. DOCUMENT TYPE: Patent CA Section: 72 (Electrochemistry) Section cross-reference(s): 23, 25, 45 Ketones (e.g., benzylmethylketone) and aldehydes are electrochem. synthesized by redn. of org. halides (e.g., benzyl halide) in the presence of acid anhydrides (e.g., acetic anhydride) in an electrolysis cell contg. an org. solvent (e.g., DMF) and an inert electrolyte (e.g., Bu4NBF4). The anode is a metal chosen from Mg, Al, Zn, and their alloys. The process is applicable to cells with 31 compartment. .

Preparation of veratryl cyanide, a pharmaceutical intermediate

Preparation of veratryl cyanide, a pharmaceutical intermediate. Mueller, Josef; Wiersdorff, Walter Wielant; Burst, Wolfram; Dralle, Heinz; Schaeffner, Ernst; Steinkamp, Rolf (BASF A.-G. , Fed. Rep. Ger.). Ger. Offen. DE 3527338 A1 5 Feb 1987, 4 pp. (Germany) CODEN: GWXXBX. CLASS: ICM: C07C121-75. ICS: C07C120-04. APPLICATION: DE 85-3527338 31 Jul 1985. DOCUMENT TYPE: Patent CA Section: 25 (Benzene, Its Derivatives, and Condensed Benzenoid Compounds) Section cross-reference(s): 63 Veratryl cyanide (I), an important pharmaceutical intermediate, is prepd. by chloromethylation of veratrole (II) and subsequent treatment of the resulting chloride with NaCN. A soln. contg. PhMe 87, H2O 2.4, 1,2,4-(MeO)2ClCH2C6H3 18.65, NaI 0.12, Et3N 0.12, Me2CO 10, and NaCN 6 parts was heated for 3.5 h at 85°. Addn. of H2O, sepn. of the layers, and distn. gave 95% I.Except for chemicals metioned above, 93-17-4 and 7306-46-9 are also used. .