Detail of "73334-07-3"

Reference

The influence of low pH on blood-brain barrier effects of intracarotid iopromide

The influence of low pH on blood-brain barrier effects of intracarotid iopromide. Wilson, A. J.; Evill, C. A.; Sage, M. R. (Dep. Radiol., Flinders Univ. South Australia, Bedford Park, Australia). Invest. Radiol., 26(Suppl. 73334-07-3 is the cas registry number of certain chemical which is used as reagents here. 1), S113-S114 (English) 1991. CODEN: INVRAV. ISSN: 0020-9996. DOCUMENT TYPE: Journal CA Section: 8 (Radiation Biochemistry) Reducing the pH to 5.6 gave an addnl. minor effect of intracarotid iopromide on the blood-brain barrier. Even at the lower pH, however, the degree of damage was of the same order of magnitude as that found with some other nonionic contrast media. .

Mechanism of renal excretion of various x-ray contrast materials in rabbits

Mechanism of renal excretion of various x-ray contrast materials in rabbits. Zurth, Christian (Res. Lab., Schering A.-G., Berlin, Fed. Rep. Ger.). Invest.There are some reagents with their cas registry numbers 85-36-9 and 73334-07-3 are used in this study. Radiol., 19(2), 110-15 (English) 1984. CODEN: INVRAV. ISSN: 0020-9996. DOCUMENT TYPE: Journal CA Section: 8 (Radiation Biochemistry) The excretory behavior of 9 nephrotropic contrast agents with varying physicochem. properties such as charge, lipophilicity, and mol. size was investigated. Renal clearance in comparison with inulin was detd. by means of the continuous infusion method. Each contrast agent was infused at 3 dose levels in 4-6 rabbits. The investigations show that tubular transportation in proportion to glomerular filtration decreases with increasing doses of all the contrast agents. Thus, with the highest concn. in plasma, all contrast agents are eliminated at more or less the glomerular filtration rate. After administration of the low doses, the following differences are found: (1) net tubular secretion increases for the monomeric contrast agent acids with increasing lipophilicity, in the order diatrizoate x iothalamate < iodamide < acetrizoate; (2) the clearance studies do not reveal any tubular secretion or reabsorption for a hydrophilic cationic contrast agent; (3) the nonionic contrast agents do not show net secretion and the more lipophilic they are, the more they are reabsorbed; and (4) 2 dimeric contrast agents also do not reveal any tubular secretion. They seem to be reabsorbed more than monomers with the same charge. .