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Detail of > 73384-59-5

  • CAS Number:
  • 73384-59-5
  • Name:
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-,(6R,7R)-

  • Superlist Name:
  • Ceftriaxone
  • Formula:
  • C18H18N8O7S3
  • Molecular Structure:
  • Synonyms:
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-,[6R-[6a,7b(Z)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-,(6R,7R)- (9CI);Biotrakson;Rocefin;Rocephalin;Rophex;
  • Molecular Weight:
  • 554.58
  • EINECS:
  • 277-405-6
  • Density:
  • 1.96 g/cm3
  • Melting Point:
  • 155 °C
  • Hazard Symbols:
  • HarmfulXn
  • Risk Codes:
  • 42/43
  • Safety:
  • 22-24-37-45Details
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    Reference

    Long-lasting new cephalosporins: study of the pharmacokinetics of cefpiramide and ceftriaxone
    Long-lasting new cephalosporins: study of the pharmacokinetics of cefpiramide and ceftriaxone. Kawaguchi, Hiroshi; Nakayama, Kazushige; Akieda, Yozo; Kawamura, Hiroyuki; Yamaji, Emiko (Sch. Med., Nihon Univ., Tokyo, Japan). Rinsho Yakuri, 15(1), 55-6 (Japanese) 1984. CODEN: RIYADS. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) The half-lives of cefpiramide (I) [70797-11-4] and ceftriaxone (II) [73384-59-5] in human blood serum were 5 and 7.7 h, resp., which were greater than those of commonly known cephalosporin antibiotics. The detn. of drug levels by high-performance liq. chromatog. was more rapid than detn. by bioassay.
    Ceftriaxone: a review of its antibacterial activity, pharmacological properties and therapeutic use
    Ceftriaxone: a review of its antibacterial activity, pharmacological properties and therapeutic use. Richards, Deborah M.; Heel, R. C.; Brogden, R. N.; Speight, T. M.; Avery, G. S. (ADIS Drug Inf. Serv., Auckland, N. Z.). Drugs, 27(6), 469-527 (English) 1984. CODEN: DRUGAY. ISSN: 0012-6667. DOCUMENT TYPE: Journal; General Review CA Section: 1 (Pharmacology) Section cross-reference(s): 10 A review on ceftriaxone (I) [73384-59-5] with many refs.

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