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Detail of "73963-72-1"

  • MSDS Download
  • CAS Number:
  • 73963-72-1
  • Name:

  • Cilostazol

  • Molecular Structure:
  • Formula:
  • C20H27N5O2
  • Molecular Weight:
  • 369.52
  • Deleted CAS:
  • 89332-50-3
  • Synonyms:
  • 6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one;Pletal;OPC 13013;Cilostazol (JAN/USAN);2(1H)-Quinolinone,6-[4-(1-cyclohexyl-1Htetrazol- 5-yl)butoxy]-3,4-dihydro-;Pletal (TN);Cilostazole;Cilostal;
  • Density:
  • 1.34 g/cm3
  • Melting Point:
  • 159-160 °C
  • Boiling Point:
  • 664.7 °C at 760 mmHg
  • Flash Point:
  • 355.8 °C
  • Solubility:
  • DMSO: 18 mg/mL, soluble
  • Appearance:
  • off-white solid
  • Hazard Symbols:
  • IrritantXi
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CAS No.73963-72-1 CilostazolCompetitive Product

Product name : Cilostazol CAS NO. : [73963-72-1] Synonyms : 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone Additional name: 6-[4-(1-Cyclohexyl-5-tetrazolyl)butoxy]-1,2,3,4- tetrahydro-2-oxoquinolinone Molecular Formula : C20H27N5O2 Molecular Weight

Supplier:NINGBO SINOVA I/E CORP. [ China (Mainland)]

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CAS No.73963-72-1 Cilostazol

  Appearance:solidStorage:Store at RT  Transportation:by sea  Application:platelet agg...

melting point：159-160°C density:98%

Min. Order:1Kilogram

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Cilostazole

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Cilostazol;

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Cilostazol,Cas#73963-72-1

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CAS No.73963-72-1 Cilostazol

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Cilostazol

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CAS No.73963-72-1 Cilostazol

white powder

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Cilostazol GMP SFDA

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CAS No.73963-72-1 Cilostazol

Assay:>99%Storage:at -20℃ 2 ye...

M.Wt: 369.46 Formula: C20H27N5O2 Solubility: Unknown

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Cilostazol is a medication used in the alleviation of the symptom of intermittent claudication in individuals with peripheral vascular disease.

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CAS No.73963-72-1 Cilostazol

Product Name: Cilostazol CAS: 73963-72-1 Specification: ≥99% Molecular Frumla: C20H27O2N5 Standsrds Appearance: White powder Mekting piont: 157°C-162°C Assay(HPLC): ≥99.5% Use for: Packging: In 25KG paper drum

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Cilostazol

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CILOSTAZOL

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Supplier:Ipca Laboratories Limited [ India]

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Reference

Physicochemical properties and stability of cilostazol
Physicochemical properties and stability of cilostazol. Shimizu, T.; Osumi, T.; Niimi, K.; Nakagawa, K. (Tokushima Res. Inst., Otsuka Pharm. Co., Ltd., Tokushima 771-01, Japan). Arzneim.-Forsch., 35(7A), 1117-23 (English) 1985. CODEN: ARZNAD. ISSN: 0004-4172. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) The physicochem. properties of cilostazol (OPC-13013) (I) [73963-72-1], a new potential antithrombotic and vasodilating drug, were studied by clarifying its elemental compn., m.p., and physicochem. and spectral properties. Anal. test methods such as HPLC and TLC were established for use in stability tests, and the stability study of I in an aq. soln. (acid and base) and in a solid form were carried out. I was stable with no changes from the initial values.
Phase I study of cilostazol
Phase I study of cilostazol. Safety evaluation at increasing single doses in healthy volunteers. Niki, T.; Mori, H. (Sch. Med., Tokushima Univ., Tokushima, Japan). Arzneim.-Forsch., 35(7A), 1173-85 (English) 1985. CODEN: ARZNAD. ISSN: 0004-4172. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) The safety and blood concns. of the novel synthetic platelet aggregation inhibitor cilostazol (I) [73963-72-1] were detd. in healthy volunteers. The drug was orally administered to the subjects once at successive dose increments of 25, 50, 75, 100, 150, 200 and 300 mg. Subjective complaints were headache at 75 mg in 1 of 4 subjects and dull headache at 75 mg in 2 of 4. Each of these symptoms was also seen at higher doses in 1 or 2 of 4 subjects. Clin. lab. values, blood pressure and heart rate were normal. Blood concns. of the drug peaked after 3 to 4 h, the levels declining with half-lives of 2.6 to 3.2 h in the a-phase and 19.5 to 25.5 h in the b-phase. The decline was generally prompt. The av. peak concns. were 283.7, 663.4, 540, 823.6, 1110.4, 1129.2 and 1623.9 mg/mL at the above doses, resp. The effect of food on the blood concn. was also studied; however, the areas under the curve did not indicate significant differences between the fed and fasted subjects.
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