Detail of "74434-59-6"

Reference

A comparison of the effects of corticotropin-releasing factor and sauvagine on food intake

A comparison of the effects of corticotropin-releasing factor and sauvagine on food intake. Gosnell, Blake A.; Morley, John E.; Levine, Allen S. (Neuroendocr. Res. Lab., Minneapolis VA Med. Cent., Minneapolis, MN 55417, USA). Pharmacol., Biochem. 9015-71-8 and 74434-59-6 which are cas registry numbers are also used here. Behav., 19(5), 771-5 (English) 1983. CODEN: PBBHAU. ISSN: 0091-3057. DOCUMENT TYPE: Journal CA Section: 2 (Mammalian Hormones) CRF [9015-71-8] and sauvagine (SVG) [74434-59-6] when administered intracerebroventricularly to rats both reduced spontaneous feeding as well as feeding induced by deprivation or the administration of ethylketocyclazocine (EKC). For spontaneous- and EKC-induced feeding, SVG produced a larger and longer-lasting suppressive effect than did CRF. Both peptides produced a conditioned taste aversion when paired with a novel saccharin taste. As with the feeding effects, SVG produced a stronger aversion than did CRF. These studies further establish the similarity between CRF and SVG and suggest that they may have a disruptive effect on feeding. .

Solid-phase synthesis of sauvagine-(17-40)

Solid-phase synthesis of sauvagine-(17-40). Santangelo, Francesco; Montecucchi, Pier Carlo; Gozzini, Luigia; Henschen, Agnes (Chem. Res.In this study， 74434-59-6 and 88831-26-9 are also used. Dep., Farmitalia Carlo Erba, S.p.A., Milan, Italy). Int. J. Pept. Protein Res., 22(3), 348-54 (English) 1983. CODEN: IJPPC3. ISSN: 0367-8377. DOCUMENT TYPE: Journal CA Section: 34 (Amino Acids, Peptides, and Proteins) The title peptide (I) was prepd. by the solid-phase method on a benzhydrylamine resin. I was purified by gel filtration and had an acceptable degree of homogeneity according to electrophoresis, chromatog., and automated Edman degrdn. anal. I was devoid of any sauvagine activity on the circulatory system and endocrine glands, and it exhibited a weak effect on gastric emptying delay. .