CAS No.75-43-4,Dichloromonofluoromethane Suppliers,MSDS download

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Basic Information

Molecular Structure:
CAS No.:	75-43-4
Name:	Dichloromonofluoromethane
Article Data:	57

Formula:	CHCl₂F
Molecular Weight:	102.923
Synonyms:	AF 22;AF22 (fluorocarbon);Algofrene Type 5;Arcton 7;CFC 21;Dichlorofluoromethane;Dichloromonofluoromethane;F 21;F 21 (fluorocarbon);FC 21;Fluorocarbon-21;Fluorodichloromethane;Freon 21;Genetron 21;HCFC 21;Monofluorodichloromethane;R 21;R 21 (refrigerant);
EINECS:	200-869-8
Density:	1.397 g/cm³
Melting Point:	-135 °C
Boiling Point:	8.9 °C at 760 mmHg
Flash Point:	130-132°C/3mm
Solubility:	Slightly soluble in water
Appearance:	COLOURLESS GAS OR COMPRESSED LIQUEFIED GAS, WITH CHARACTERISTIC ODOUR.
Hazard Symbols:	N
Risk Codes:	59
Safety:	59
PSA:	0.00000
LogP:	1.71710

Synthetic route

: 87375-48-2
1,1-dichloroperfluoro-2-butanone

A: 75-43-4
Dichlorofluoromethane

B: 141-53-7
sodium formate

C: 378-77-8
sodium pentafluoropropionate

Conditions

Conditions	Yield
With sodium hydroxide In water Product distribution;	A 33.5% B n/a C 84.5%

...Expand

: 75-69-4
trichlorofluoromethane

: 75-43-4
Dichlorofluoromethane

Conditions

Conditions	Yield
With N,N,N,N,N,N-hexamethylphosphoric triamide In N,N-dimethyl-formamide at 20℃; for 0.5h;	20%
With ruthenium(II) bis(triphenylphosphine) dichloride; hydrogen In ethanol; toluene at 25℃; for 12h; Product distribution; also carbon tetrachloride; also in the presence of RuCl2(dppe)2 or RuHCl(PPh3)2; other solvents; var. time and temp.;
titanium pH=7; Kinetics;
With formate; titanium(IV) oxide In various solvent(s) at 23℃; for 1h; pH=5.9; Kinetics; Further Variations:; pH-values; Irradiation;

: 75-09-2
dichloromethane

: 75-43-4
Dichlorofluoromethane

Conditions

Conditions	Yield
With uranium hexafluoride
With hydrogen fluoride; lithium fluoride at 0℃;

: 67-66-3
chloroform

: 75-43-4
Dichlorofluoromethane

Conditions

Conditions	Yield
With antimonypentachloride; antimony(III) fluoride unter Druck;
With hydrogen fluoride; antimonypentachloride; antimony(III) chloride
With hydrogen fluoride; titanium(IV) fluoride at 127℃;

: 75-09-2
dichloromethane

A: 75-10-5
Difluoromethane

B: 593-70-4
R32

C: 75-45-6
Chlorodifluoromethane

D: 75-43-4
Dichlorofluoromethane

E: 75-71-8
Dichlorodifluoromethane

F: 75-69-4
trichlorofluoromethane

Conditions

Conditions	Yield
With xenon difluoride for 48h; Ambient temperature; other halogenocarbons; var. reaction time;

...Expand

: 75-45-6
Chlorodifluoromethane

A: 75-46-7
trifluoromethan

B: 75-43-4
Dichlorofluoromethane

C: 67-66-3
chloroform

Conditions

Conditions	Yield
zinc aluminate at 300℃; Product distribution; other temperature;

...Expand

: 67-66-3
chloroform

A: 75-46-7
trifluoromethan

B: 75-45-6
Chlorodifluoromethane

C: 75-43-4
Dichlorofluoromethane

Conditions

Conditions	Yield
With antimony tetrachloride fluoride at 100℃; Kinetics; Product distribution; kinetic behaviour of different fluorinated antimony compound in fluorination (SbCl4F, SbCl5 + SbF3Cl2, SbCl5 + SbF5, SbCl5 + SbF3) at different reaction times;
With antimony tetrachloride fluoride at 100℃; under 7600 Torr; Kinetics; Product distribution; Equilibrium constant; kinetic at three different temperatures (85, 100, 115 deg C) and at different pressures ( 7.3, 8.0, 10.0, 10.5, 13.0, 13.8 atm);
With hydrogen fluoride; antimonypentachloride at 70 - 90℃; under 10746.4 - 10953.3 Torr; Product distribution / selectivity; Heating / reflux;

...Expand

: 70393-08-7
(dichloro-fluoro-methyl)-tris-dimethylamino-phosphonium; chloride

A: 75-43-4
Dichlorofluoromethane

B: 75-69-4
trichlorofluoromethane

C: 353-58-2
bromodichlorofluoromethane

D: 353-55-9
dibromochlorofluoromethane

Conditions

Conditions	Yield
With potassium fluoride; bromine In various solvent(s)	A 25 % Spectr. B 15 % Spectr. C 42 % Spectr. D 5 % Spectr.

...Expand

: 75-09-2
dichloromethane

A: 75-10-5
Difluoromethane

B: 593-70-4
R32

C: 75-45-6
Chlorodifluoromethane

D: 75-43-4
Dichlorofluoromethane

E: 75-71-8
Dichlorodifluoromethane

Conditions

Conditions	Yield
With osmium pentafluoride oxide Product distribution; other transition-metal oxide fluorides;

...Expand

: 79-51-6
1,1,3,3-tetrachloro-1,3-difluoro-2-propanone

: 67-64-1
acetone

A: 75-43-4
Dichlorofluoromethane

B: 1717-00-6
HCFC-141b

C: 75-69-4
trichlorofluoromethane

D: 2317-91-1
1-chloro-1-fluoroethane

E: 75-35-4
1,1-Dichloroethylene

F: 76-12-0
CFC-112a

Conditions

Conditions	Yield
With propene; sulphur hexafluoride for 0.5h; Rate constant; Ambient temperature; Irradiation; also with acetone-d6;

...Expand

Total:24 Page 1 of 1 1

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Consensus Reports

Reported in EPA TSCA Inventory.

Standards and Recommendations

OSHA PEL: TWA 10 ppm
ACGIH TLV: TWA 10 ppm
DFG MAK: 10 ppm (43 mg/m³)
DOT Classification: 2.2; Label: Nonflammable Gas

Analytical Methods

For occupational chemical analysis use NIOSH: see DICHLOROFLUOROMETHANE, 2516.

Specification

The Dichlorofluoromethane is an organic compound with the formula CHCl₂F. The IUPAC name of this chemical is dichloro(fluoro)methane. With the CAS registry number 75-43-4, it is also named as methane, dichlorofluoro-. The product's categories are Refrigerants; Organics. Besides, it should be stored in a cool and ventilated place. It is used as a refrigerant.

Physical properties about Dichlorofluoromethane are: (1)ACD/LogP: 1.40; (2)ACD/LogD (pH 5.5): 1.4; (3)ACD/LogD (pH 7.4): 1.4; (4)ACD/BCF (pH 5.5): 6.83; (5)ACD/BCF (pH 7.4): 6.83; (6)ACD/KOC (pH 5.5): 137.75; (7)ACD/KOC (pH 7.4): 137.75; (8)Index of Refraction: 1.366; (9)Molar Refractivity: 16.5 cm³; (10)Molar Volume: 73.6 cm³; (11)Polarizability: 6.54×10^-24cm³; (12)Surface Tension: 19.9 dyne/cm; (13)Density: 1.397 g/cm³; (14)Enthalpy of Vaporization: 24.65 kJ/mol; (15)Boiling Point: 8.9 °C at 760 mmHg; (16)Vapour Pressure: 1340 mmHg at 25°C.

Preparation: this chemical can be prepared by trichloro-fluoro-methane. This reaction will need reagent HMPT and solvent dimethylformamide. The reaction time is 30 min with reaction temperature of 20 °C. The yield is about 20%.

Uses of Dichlorofluoromethane: it can be used to produce 7-chlor-7-fluor-1-methylbicyclo[4.1.0]heptan . It will need reagent 55percent KOH, 18-crown-6 with reaction time of 1 hour. The yield is about 80%.

You can still convert the following datas into molecular structure:
(1)SMILES: ClC(Cl)F
(2)InChI: InChI=1/CHCl2F/c2-1(3)4/h1H
(3)InChIKey: UMNKXPULIDJLSU-UHFFFAOYAU
(4)Std. InChI: InChI=1S/CHCl2F/c2-1(3)4/h1H
(5)Std. InChIKey: UMNKXPULIDJLSU-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LCLo	inhalation	10pph/1H (100000ppm)		Fluorine Chemistry Reviews. Vol. 1, Pg. 197, 1967.
mouse	LC50	inhalation	> 800gm/m³/2H (800000mg/m³)	BEHAVIORAL: TREMOR BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 20(11), Pg. 38, 1976.
rat	LC50	inhalation	49900ppm/4H (49900ppm)		"Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986Vol. 5, Pg. 187, 1986.