Detail of "75007-16-8"
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Reference
- Methods of synthesis of pentoxiphylline
- Methods of synthesis of pentoxiphylline. Sidzhakova, D.; Peikov, P.; Gagauzov, I. (Nauch. Inst. Farmakol. Farm., MA, Sofia, Bulg.). Farmatsiya (Sofia), 38(4), 1-5 (Bulgarian) 1988. CODEN: FMTYA2. There are some commonly used reagents like 75007-16-8 in this article. ISSN: 0428-0296. DOCUMENT TYPE: Journal CA Section: 26 (Biomolecules and Their Synthetic Analogs) 1-(3-Iodopropyl)theobromine (I; R = iodo) (II) condensed with (MeCO)2CH2 or MeCOCH2CO2Et in refluxing Me2CO contg. K2CO3 for 30 h to give 35.8-37.2% title compd., I (R = MeCOCH2), after treatment with 5% aq. NaOH and neutralization. The intermediate I [R = (MeCO)2CH, HO] were also isolated in £20% yield by varying the base, solvent and C acid used. Refluxing II 1 h with NaOMe in MeOH gave 61% I (R = MeO). .


