Reference

Effect of the antibiotics kanamycin, fusidin, and tetracycline on the chromosomal apparatus of human embryonal fibroblast tissue cultures

Effect of the antibiotics kanamycin, fusidin, and tetracycline on the chromosomal apparatus of human embryonal fibroblast tissue cultures. Kiryushchenkov, A. P.; Yankova, M. F.; Niyazova, M. A. (Vses. Nauchno-Issled. Inst. Akush. Ginekol., Moscow, USSR). Akush. Ginekol. (Moscow), (12), 10-13 (Russian) 1976. CODEN: AKGIAO. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Kanamycin [8063-07-8] caused chromosomal aberrations in cultured human embryonic fibroblasts only at high concns. (6000-12,000 IU/mL), i.e. concns. which would never occur in the blood stream. 60-54-8 and 8063-07-8 which are cas registry numbers of substances are two of reagents here. However, fusidin [751-94-0] and tetracycline (I) [60-54-8] caused aberrations at 30 and 2 .mu.g/mL, resp. Thus, caution should be used in administering these antibiotics to pregnant women. .

Cholestyramine induced antibiotic malabsorption

Cholestyramine induced antibiotic malabsorption. Parsons, R. L.; Paddock, Gillian M.; Hossack, Gillian M. (Dep. Clin. 18323-44-9 and 15686-71-2 are cas registry numbers. These chemicals are also mentioned in this article. Pharmacol., Guy's Hosp. Med. Sch., London, Engl.). Chemother., Proc. Int. Congr. Chemother., 9th, Meeting Date 1975, Volume 4, 191-8. Edited by: Williams, John David; Geddes, Alexander M. Plenum: New York, N. Y. (English) 1976. CODEN: 35DFA6. DOCUMENT TYPE: Conference CA Section: 1 (Pharmacodynamics) Cholestyramine [11041-12-6] administered to humans for the treatment of hyperlipidemia caused malabsorption of simultaneously administered cephalexin [15686-71-2], clindamycin [18323-44-9], Na fusidate [751-94-0], sulfamethoxazole [723-46-6], and trimethoprim [738-70-5], suggesting that these antibiotics should not be administered simultaneously with cholestyramine. .