Detail of "7530-27-0"

Reference

Process for the preparation of polyalkoxylated aromatic compounds

Process for the preparation of polyalkoxylated aromatic compounds. Huet, Michel; Nobel, Dominique (Rhone-Poulenc Chimie, Fr.). Eur. Pat. Appl. EP 463946 A1 2 Jan 1992, 20 pp. DESIGNATED STATES: R: DE, FR, GB, IT, NL. (European Patent Organization). CODEN: EPXXDW. CLASS: ICM: C07C047-575. ICS: C07C045-64; C07C041-16. APPLICATION: EP 91-401683 21 Jun 1991. PRIORITY: FR 90-8071 27 Jun 1990; FR 90-15000 30 Nov 1990. DOCUMENT TYPE: Patent CA Section: 25 (Benzene, Its Derivatives, and Condensed Benzenoid Compounds) The title compds. were prepd. by treating an arom. 12069-69-1 and 7530-27-0 which are cas registry numbers are also used here. compd. bearing at least one halogen atom and at least one OH group with an alk. or alk. earth alkoxide in presence of a Cu-contg. catalyst and a cocatalyst chosen from org. carbonates, organometallic carbonates, or CO2. Next, direct O-alkylation of the OH group(s) was realized with alkylating agents: alkyl halides, dialkyl sulfates, dialkyl carbonates. E.g., a mixt. of 173.2 g 5-bromo-4-hydroxy-3-methoxybenzaldehyde, 162 g NaOMe, 1785 cm3 MeOH, 8.3 g CuCO3.Cu(OH)2, and 16 g CO2 was stirred for 4 h at 125°. The mixt. was then treated with 150 g MeCl at 120° for 3 h to give 100% conversion and 92% 3,4,5-trimethoxybenzaldehyde. .