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7542-37-2

Basic Information
CAS No.: 7542-37-2
Name: paromomycin
Article Data: 3
Molecular Structure:
Molecular Structure of 7542-37-2 (paromomycin)
Formula: C23H45 N5 O14
Molecular Weight: 615.635
Synonyms: D-Streptamine,O-2-amino-2-deoxy-a-D-glucopyranosyl-(1®4)-O-[O-2,6-diamino-2,6-dideoxy-b-L-idopyranosyl-(1®3)-b-D-ribofuranosyl-(1®5)]-2-deoxy-; Hydroxymycin (6CI); Streptamine, O-2,6-diamino-2,6-dideoxy-b-L-idopyranosyl-(1®3)-O-b-D-ribofuranosyl-(1®5)-O-[2-amino-2-deoxy-a-D-glucopyranosyl-(1®4)]-2-deoxy- (8CI); Zygomycin A1 (7CI); Aminosidin;Aminosidine; Aminosidine I; Amminosidin; Antibiotic 2230D; Antibiotic 503-3;Antibiotic SF 767B; Catenulin; Crestomycin; Gabbromicina; Gabbromycin;Gabromycin; Humycin; Monomycin A; Neomycin E; Paromomycin; Paromomycin I;Paromomycine; Paucimycin; Quintomycin C; R 400
Density: 1.64g/cm3
Boiling Point: 939.8ºC at 760 mmHg
Flash Point: 522.2ºC
Safety: Moderately toxic by ingestion, intramuscular, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx.
PSA: 347.32000
LogP: -5.36020
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Toxicity Data With Reference

1.   

orl-rat LD50:21,620 mg/kg

    NKRZAZ    Chemotherapy (Tokyo). 16 (1968),124.
2.   

scu-rat LD50:1010 mg/kg

    ANTCAO    Antibiotics and Chemotherapy. 12 (1962),243.
3.   

ims-rat LD50:1200 mg/kg

    NKRZAZ    Chemotherapy (Tokyo). 16 (1968),124.
4.   

orl-mus LD50:2275 mg/kg

    85ERAY    Antibiotics: Origin, Nature, and Properties. 1 (1978),674.
5.   

ipr-mus LD50:930 mg/kg

    85FZAT    Index of Antibiotics from Actinomycetes Umezawa, H., et al., eds.,Tokyo, Japan.: University of Tokyo Press,1967,332.

Safety Profile

Moderately toxic by ingestion, intramuscular, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx.