Welcome to LookChem.com Sign In|Join Free
  • or
Home > Pharmaceutical > 75530 > 

75530-68-6

Basic Information
CAS No.: 75530-68-6
Name: Nilvadipine
Article Data: 11
Molecular Structure:
Molecular Structure of 75530-68-6 (Nilvadipine)
Formula: C19H19N3O6
Molecular Weight: 385.376
Synonyms: CL 287389;Escor;FK 235;FR 34235;Nivadil;Nivadip;SKF 102362;dl-Nilvadipine;
EINECS: 805-887-5
Density: 1.32 g/cm3
Melting Point: 148-150 °C
Boiling Point: 526.7 °C at 760 mmHg
Flash Point: 272.3 °C
Appearance: yellow prisms
Hazard Symbols: Xn
Risk Codes: 22
PSA: 134.24000
LogP: 3.30988
Synthetic route
1452166-70-9

isopropyl 2-hydroxyiminomethyl-3-methoxycarbonyl-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-5-carboxylate

75530-68-6

nilvadipine

Conditions
ConditionsYield
With acetic anhydride; potassium carbonate In dimethyl sulfoxide at 10 - 50℃; for 5h;85.1%

sodium 2-cyano-5-isopropoxycarbonyl-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate

A

75530-68-6

nilvadipine

B

145220-80-0

isopropyl 2-carbamoyl-3-methoxycarbonyl-6-methyl-4-(3-nitrophenyl)-1, 4-dihydropyridine-5-carboxylate

Conditions
ConditionsYield
With hydrogenchloride 1.) AcOEt, 2.) AcOEt, ether; Yield given. Multistep reaction. Yields of byproduct given;
75530-60-8

isopropyl 2-formyl-3-methoxycarbonyl-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-5-carboxylate

75530-68-6

nilvadipine

Conditions
ConditionsYield
With hydroxylamine hydrochloride; sodium acetate; acetic anhydride 1.) AcOH, RT, 2.5 h, 2.) AcOH, a) RT, 1.5 h, b) 95 deg C - 100 deg C, 4 h; Yield given. Multistep reaction;
Multi-step reaction with 2 steps
1: hydroxylamine hydrochloride; sodium acetate / water; methanol / 4 h / 20 °C
2: acetic anhydride; potassium carbonate / dimethyl sulfoxide / 5 h / 10 - 50 °C
View Scheme
39562-25-9

3-oxo-2-(3-nitrophenylmethylene)butanoic acid isopropyl ester

4-Amino-3-imino-butyric acid methyl ester; compound with acetic acid

75530-68-6

nilvadipine

Conditions
ConditionsYield
With sodium methylate In isopropyl alcohol Heating;
542-08-5

isopropyl acetoacetate

75530-68-6

nilvadipine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 65 percent / piperidinium acetate / propan-2-ol / 10 h / 45 - 55 °C
2: sodium methoxide / propan-2-ol / Heating
View Scheme
99-61-6

3-nitro-benzaldehyde

75530-68-6

nilvadipine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 65 percent / piperidinium acetate / propan-2-ol / 10 h / 45 - 55 °C
2: sodium methoxide / propan-2-ol / Heating
View Scheme
60705-25-1

4,4-dimethoxy-3-oxo-butyric acid methyl ester

75530-68-6

nilvadipine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: piperidine / benzene / 3 h / Heating
2: 51.1 percent / 8.5 h / 95 - 120 °C
3: 95.4 percent / 6 N aq. HCl / acetone / 1 h / Ambient temperature
4: 1.) NH2OH*HCl, NaOAc, 2.) Ac2O / 1.) AcOH, RT, 2.5 h, 2.) AcOH, a) RT, 1.5 h, b) 95 deg C - 100 deg C, 4 h
View Scheme
14205-46-0

isopropyl 3-aminocrotonate

75530-68-6

nilvadipine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 51.1 percent / 8.5 h / 95 - 120 °C
2: 95.4 percent / 6 N aq. HCl / acetone / 1 h / Ambient temperature
3: 1.) NH2OH*HCl, NaOAc, 2.) Ac2O / 1.) AcOH, RT, 2.5 h, 2.) AcOH, a) RT, 1.5 h, b) 95 deg C - 100 deg C, 4 h
View Scheme
99-61-6

3-nitro-benzaldehyde

platinum black

platinum black

75530-68-6

nilvadipine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: piperidine / benzene / 3 h / Heating
2: 51.1 percent / 8.5 h / 95 - 120 °C
3: 95.4 percent / 6 N aq. HCl / acetone / 1 h / Ambient temperature
4: 1.) NH2OH*HCl, NaOAc, 2.) Ac2O / 1.) AcOH, RT, 2.5 h, 2.) AcOH, a) RT, 1.5 h, b) 95 deg C - 100 deg C, 4 h
View Scheme
67448-15-1

(E,Z)-methyl 4,4-dimethoxy-2-(3-nitrobenzylidene)acetoacetate

75530-68-6

nilvadipine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 51.1 percent / 8.5 h / 95 - 120 °C
2: 95.4 percent / 6 N aq. HCl / acetone / 1 h / Ambient temperature
3: 1.) NH2OH*HCl, NaOAc, 2.) Ac2O / 1.) AcOH, RT, 2.5 h, 2.) AcOH, a) RT, 1.5 h, b) 95 deg C - 100 deg C, 4 h
View Scheme
  • Display:default sort

    New supplier

  • Nilvadipine Manufacturer/High quality/Best price/In stock

  • Casno:

    75530-68-6

    Nilvadipine Manufacturer/High quality/Best price/In stock

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 3.0-3.0

    DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

    Dayang Chem (Hangzhou) Co.,Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredi

  •  Dayang Chem (Hangzhou) Co.,Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-88938639

    Address:9/F, Unit 2 Changdi Torch Building, 259# WenSan Road, Xihu District, Hangzhou City 310012, P.R.China

       Inquiry Now

  • High quality Nilvadipine  supplier in China

  • Casno:

    75530-68-6

    High quality Nilvadipine supplier in China

    Min.Order: 0 Metric Ton

    FOB Price:  USD $ 0.0-0.0

    Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

    Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional

  •  Simagchem Corporation

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-592-2680277

    Address:21/F Hualong Office Building,No.6 Hubin East Road, Xiamen,China

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 5 Kiloliter

    FOB Price:  USD $ 1.2-5.0

    Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

    Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Fine chemicals, Active pharmaceutical ingredients(APIs), Veterinary, In

  •  Chemwill Asia Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:021-51086038

    Address:High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China

       Inquiry Now

  • TIANFUCHEM-- 75530-68-6--High purity Nilvadipine in stock

  • Casno:

    75530-68-6

    TIANFUCHEM-- 75530-68-6--High purity Nilvadipine in stock

    Min.Order: 1 Metric Ton

    FOB Price:  USD $ 2000.0-2000.0

    TIANFUCHEM-- 75530-68-6--High purity Nilvadipine in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business r

    Our company engages in Electronic chemicals such as OLED,Photoresist chemical,Electrolyte additive and Intermediate Pharmaceutical production; development of noble metal catalysts,

  •  Henan Tianfu Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-371-55170693/55170694

    Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 9.0-99.0

    Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

    Our company specializes in processing and selling chemical raw materials, chemical th Asia, Europe, America, Africa and other more than 20 countries and regions. ? Companies adheri

  •  Hebei Nengqian Chemical Import and Export Co., LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86 15632961819

    Address:hebei

       Inquiry Now

  • Pharmaceutical Grade CAS 75530-68-6 with competitive price

  • Casno:

    75530-68-6

    Pharmaceutical Grade CAS 75530-68-6 with competitive price

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 139.0-210.0

    WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

    Zhuo Zhou Wen Xi Import and Export Co., Ltd. is a company mainly engaged in the export of pharmaceutical raw materials. Its parent company is (Wen Xi Pharma), including three subs

  •  Zhuozhou Wenxi import and Export Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-13111626072

    Address:Room 1710, Baoxin International Phase I, 19 Guanyun East Road, Zhuozhou, Hebei

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 40.0-45.0

    1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

    Hebei Sankai Chemical Technology Co., Ltd. is a new chemical enterprise integrating the research, manufacturing and supply of chemicals. Located in the beautiful "cattle city" Xing

  •  Hebei Sankai Chemical Technology Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86 15932099601

    Address:hebei

       Inquiry Now

  • Nilvadipine CAS:75530-68-6

  • Casno:

    75530-68-6

    Nilvadipine CAS:75530-68-6

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    Nilvadipine CAS:75530-68-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates

    Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, speciali

  •  Qingdao Beluga Import and Export Co., LTD

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+8613854236000

    Address:qingdao

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

    Shandong Hanjiang Chemical Co., Ltd. is located in Qilu Petrochemical Industrial Park, Zibo City, Shandong Province, involving pesticide, medicine, chemical industry, coating, dy

  •  Shandong Hanjiang Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:18369939125

    Address:95A, Xingyuan East Road, Zhangdian District

       Inquiry Now

  • NILVADIPINE

  • Casno:

    75530-68-6

    NILVADIPINE

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

    AFINE CHEMICALS LIMITED is specialized in the fine chemicals and pharmaceuticals and we have enjoyed great popularity in world markets. Since 2005, we have been rapidly growing to

  •  Afine Chemicals Limited

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-85134551

    Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China

       Inquiry Now

  • Factory Supply nilvadipine

  • Casno:

    75530-68-6

    Factory Supply nilvadipine

    Min.Order: 0 Metric Ton

    FOB Price:  USD $ 0.0-0.0

    The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

    Ality Chemical, established in 2007, is a comprehensive Chemical Production&Supply Group with Patent Technology as its core. Ality Chemical operates sales branches in Shanghai, Xia

  •  Ality Chemical Corporation

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:0513-87616220

    Address:Fine chemical industry park, Nantong,Jiangsu

       Inquiry Now

  • High quality Nilvadipine

  • Casno:

    75530-68-6

    High quality Nilvadipine

    Min.Order: 10 Gram

    FOB Price:  USD $ 100.0-100.0

    Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

    Hangyu Biotech is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and O

  •  Zibo Hangyu Biotechnology Development Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-15965530500

    Address:Room1701, Tianxing Building,Licheng district, jinan, Shandong, China

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    supplier in China Appearance:yellow prisms Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:100g/bottle,1kg/bottle,25kg/drum or as per your request Application: Used as an antihypertensive and antianginal Trans

    Hangzhou Yunuo Chemical Co., Ltd. is located in Hangzhou City, China We are specialized in fine chemicals and basic chemical auxiliary materials, Organic compounds, rubber

  •  HANGZHOU YUNUO CHEMICAL CO.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:0571-83715115

    Address:hangzhou

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0

    Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

    TaiChem was established in 2015 and registered in China medical city - Taizhou, Jiangsu Province. The company has about 1800 square meters of class A plant facility. TaiChem focuse

  •  TaiChem Taizhou Limited

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-0523-86810091

    Address:Changjiang Dadao 18

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

    Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns

  •  Hunan chemfish Pharmaceutical co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:0731-85567275

    Address:No.10048, xiangjiang centry bulding ,kaifu district ,changsha city ,Hunan

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:Active Pharmaceutical I

    Suzhou Health Chemicals Co., Ltd. is A Fine Chemicals Company, specializing in research, development, manufacture and distribute raw materials for pharmaceutical, healthcare, bioch

  •  Suzhou Health Chemicals Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-512-58277800

    Address:No. 338, Jingang Avenue,

       Inquiry Now

  • Nilvadipine cas no. 75530-68-6 98%

  • Casno:

    75530-68-6

    Nilvadipine cas no. 75530-68-6 98%

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

    Established in 2007, Win-Win chemical CO., Ltd is a privately held corporation headquartered in Wenzhou Longwan Industry Distric, dedicated to the global pharmaceutical companies a

  •  Win-Win chemical Co.Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:0086-577-64498589

    Address:No.49 YuShi West Road, Longwan District,325000

       Inquiry Now

  • nilvadipine

  • Casno:

    75530-68-6

    nilvadipine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

    Kono Chem Co.,Ltd is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, health food and cosmetic industries. Annually, mo

  •  Kono Chem Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:86-29-86107037-8015

    Address:No.11 Daqing Road,Lianhu District,Xi’an 710082,China

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

    GIHI CHEMICALS CO.,LIMITED, its former company is a small manufacturer who is specialized in the production of ester products which are used in the daily chemicals ,cosmetic produc

  •  GIHI CHEMICALS CO.,LIMITED

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:571-86217390

    Address:Huacai International Building,Sandun,Westlake District,Hangzhou 310030,Zhejiang,China

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0

    Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

    Jinhua huayi chemical co., ltd. has own manufacturers which focus on production of organic specialty products,Pharmaceuticals and its intermediates,fine chemcals of high purity.The

  •  JINHUA HUAYI CHEMICAL CO., LTD.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-579-82660891

    Address:47-204 No.288, Shida St., Wuchem Dist., Jinhua,Zhejiang, 321004 China

       Inquiry Now

  • 99% up by HPLC Nilvadipine 75530-68-6

  • Casno:

    75530-68-6

    99% up by HPLC Nilvadipine 75530-68-6

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Why is SINOWAY:1) Specialized in pharmaceutical and healthcare industrial since 19872) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days.4) We have warehouse in USA with quickly shipment . Application:API

    Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of ph

  •  Sinoway Industrial Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-592-583819

    Address:16/F,Huicheng Comm,Complex,No839 XiaHe Rd, Xiamen,China

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

    Located in Zhengdong New District,?Zhengzhou of Henan province, Henan Allgreen Chemical Co.,Ltd is a comprehensive high-tech modern enterprises integrating professional R&D, pro

  •  Henan Allgreen Chemical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-0371-87507775

    Address:No 260 Dongming Road,Jinshui District

       Inquiry Now

  • Nilvadipine 75530-68-6

  • Casno:

    75530-68-6

    Nilvadipine 75530-68-6

    Min.Order: 0 Metric Ton

    FOB Price:  USD $ 0.0-0.0

    Nilvadipine Nilvadipine /75530-68-6/C19H19N3O6 Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals Application:75530-68-6

    Hangzhou Jinlan Pharm-Drugs Technology Co.,Ltd is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pudon

  •  Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:+86-571-85829053

    Address:Rm A606, Fuyi Center, jianqiao street, Jianggan Area

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

    Xiamen Aeco Chemical Industrial Co., Ltd(same as Aecochem Corp.) An ISO 9001:2015 Certified Company Your Partner in China, a Professional chemical raw material supplier, our

  •  Aecochem Corp.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-592 599 8717

    Address:No 611 Sishui Road,Huli

       Inquiry Now

  • nilvadipine

  • Casno:

    75530-68-6

    nilvadipine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

    As a member of TAIHO Group,Hubei Taiho Chemical Co.,Ltd,is a professional new-type chemicals enterprise combined into research and development,production and sales.We adhere to the

  •  Hubei Taiho Chemical Co.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-18120399543

    Address:No. 49 taifeng Road,Qianjiang City,Hubei,China

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    best seller Application:API

    Xi'an Changyue Biotechnology Co., Ltd. was established in October 2003 and is located in Xi'an High-tech Industrial Development Park. It is a company specializing in the extraction

  •  Xian Changyue Biological Technology Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-029-62886900

    Address:Keji Road NO.70

       Inquiry Now

  • Nilvadipine Impurity

  • Casno:

    75530-68-6

    Nilvadipine Impurity

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

    Wuhan Circle Star Bio-medic Technology co.,Ltd is located in wuhan, the central city of China, the core of the Changjiang river economic belt and known as the "thoroughfare of nin

  •  Wuhan Circle Star Bio-medic Technology co.,Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-13437180835

    Address:Experimental Building 311-15, Nuclear Magnetic Spectrometer Industry Base, No. 128 Guanggu 7th Road, Donghu New Technology Development Zone, Wuhan (Wuhan Area, Free Trade Zone)

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    ≥98.0% Appearance:A white or almost white crystalline powder Storage:Room temperature Package:25kg/drum or as required Application:used in medicine Transportation:by sea by air express Port:China main port

    Dawn Ray is a R&D and process improvement company,which is located in Hangzhou,Zhejiang province,China. We are dealing in muti-application of pharmaceuticals(APIS),antiobics,food a

  •  Hangzhou Dawn Ray Pharmaceutical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-571-85335020

    Address:1018 Guangyin Building,No.42 E.Fengqi Road,Hangzhou,310012 China

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    best seller Application:API

    DB Biotech co., ltd is a global and professional supplier for plant extracts and functional ingredients, the company is based in XI’an city, which is famous city for the producttio

  •  DB BIOTECH CO., LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86--1829 2989 553

    Address:No.99 Road, Xi'an, China

       Inquiry Now

  • Nilvadipine cas  75530-68-6

  • Casno:

    75530-68-6

    Nilvadipine cas 75530-68-6

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Nilvadipine cas 75530-68-6Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

    Welcome to Hangzhou Fandachem Co.,Ltd (www.FandaChem.com) Hangzhou Fandachem Co.,Ltd (Fandachem),an experienced and professional China-based Fine Chemical supplier. We supply the

  •  Hangzhou Fandachem Co.,Ltd

    China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:+86-571-28800458

    Address:Room 5010, No.9 YanAn Road,Hangzhou,Zhejiang,China

       Inquiry Now

  • nilvadipine

  • Casno:

    75530-68-6

    nilvadipine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Best quality with low priceAppearance:yellow prisms Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

    Sartort Biopharma is a leading company engaging in the production of Intermediates, fine chemicals, Ionic liquids and 3D printing materials. It has such controlled subsidiaries as

  •  Hangzhou Sartort Biopharma Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-571-28069376

    Address:914-915, Bldg. 16, No. 57, Tech Park Road, Baiyang Street, Economic And Technological Development Zone

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    we produce and sell good chemicals around the world.Appearance:white power Storage:Keep it in dry,shady and cool place Package:as your requirement Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:SEA OR AIR Port:China Main Po

    Wuhan ZSC Biomedical Technology Ltd.Co, which is professional in research and sale high techology.The company located in Wuhan, We insist on the concept of "technology first, custo

  •  Wuhan ZeShanCheng Biomedical Technology Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86 17786425391

    Address:No. 399, lihua road, dongxihu district, wuhan city (17)

       Inquiry Now

  • Nilvadipine

  • Casno:

    75530-68-6

    Nilvadipine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

    Henan Kanbei Chemical Co., Ltd. is a modern high-tech chemical enterprise integrating R&D, production and sales. The company has strong technical strength, advanced equipment, stri

  •  Henan Kanbei Chemical Co.,LTD

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-152-37804566

    Address:Evergrande Future City, intersection of Zhengkai Avenue and Sixteenth Street, Kaifeng Area, Henan Pilot Free Trade Zone

       Inquiry Now

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 75530-68-6

Specification

The Nilvadipine, with the CAS registry number 75530-68-6, is also known as 5-Isopropyl 3-methyl 2-cyano-1,4-dihydro-6-methyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate. It belongs to the product categories of Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals. This chemical's molecular formula is C19H19N3O6 and molecular weight is 385.37. Its IUPAC name is called 3-O-methyl 5-O-propan-2-yl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.

Physical properties of Nilvadipine: (1)ACD/LogP: 1.72; (2)ACD/LogD (pH 5.5): 1.72; (3)ACD/LogD (pH 7.4): 1.72; (4)ACD/BCF (pH 5.5): 12.03; (5)ACD/BCF (pH 7.4): 12.03; (6)ACD/KOC (pH 5.5): 206.47; (7)ACD/KOC (pH 7.4): 206.47; (8)#H bond acceptors: 9; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 7; (11)Index of Refraction: 1.584; (12)Molar Refractivity: 97.1 cm3; (13)Molar Volume: 290 cm3; (14)Surface Tension: 57 dyne/cm; (15)Density: 1.32 g/cm3; (16)Flash Point: 272.3 °C; (17)Enthalpy of Vaporization: 80.11 kJ/mol; (18)Boiling Point: 526.7 °C at 760 mmHg; (19)Vapour Pressure: 3.5E-11 mmHg at 25°C.

Preparation: this chemical can be prepared by 3-nitrobenzaldehyde, piperidine, 4,4 - dimethoxy methyl acetoacetate and acetic acid. This reaction will need 2-amino-2-crotonic acid isopropyl.

Uses of Nilvadipine: it is a calcium channel blocker (CCB) for the treatment of hypertension and chronic major cerebral artery occlusion. It can be used as an antihypertensive and antianginal. it can be used as calcium antagonists of dihydropyridine. Besides, it also can be used for essential hypertension. This chemical's classification codes are Antagonist [calcium channel]; Antihypertensive agents; Calcium channel blockers; Cardiovascular Agents; Drug / Therapeutic Agent; Membrane Transport Modulators; Reproductive Effect.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(OC(C)C)\C1=C(\NC(/C#N)=C(/C(=O)OC)C1c2cccc([N+]([O-])=O)c2)C
(2)InChI: InChI=1/C19H19N3O6/c1-10(2)28-19(24)15-11(3)21-14(9-20)17(18(23)27-4)16(15)12-6-5-7-13(8-12)22(25)26/h5-8,10,16,21H,1-4H3
(3)InChIKey: FAIIFDPAEUKBEP-UHFFFAOYAX

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 3850ug/kg (3.85mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA Kiso to Rinsho. Clinical Report. Vol. 21, Pg. 1723, 1987.
dog LD50 oral 510mg/kg (510mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Kiso to Rinsho. Clinical Report. Vol. 21, Pg. 1723, 1987.
mouse LD50 intravenous 9150ug/kg (9.15mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 682, 1992.
mouse LD50 oral 1300mg/kg (1300mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Kiso to Rinsho. Clinical Report. Vol. 21, Pg. 1723, 1987.
mouse LD50 subcutaneous > 320mg/kg (320mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 682, 1992.
rat LD50 intravenous 9650ug/kg (9.65mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 682, 1992.
rat LD50 oral 1560mg/kg (1560mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Kiso to Rinsho. Clinical Report. Vol. 21, Pg. 1723, 1987.
rat LD50 subcutaneous > 1gm/kg (1000mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 682, 1992.