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7558-63-6

Basic Information
CAS No.: 7558-63-6
Name: L-GLUTAMIC ACID, MONOAMMONIUM SALT
Article Data: 3
Molecular Structure:
Molecular Structure of 7558-63-6 (L-GLUTAMIC ACID, MONOAMMONIUM SALT)
Formula: C5H9 N O4 . H3 N
Molecular Weight: 164.161
Synonyms: Glutamicacid, monoammonium salt, L- (8CI); L-Glutamic acid, monoammonium salt (9CI);Ammonium glutamate; E 624; Glutamic acid monoammonium salt; MonoammoniumL-glutamate; Monoammonium glutamate
Hazard Symbols: Xi
Risk Codes: R36/37/38
Safety: Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic fumes including NOx and NH3. See also MONOSODIUM GLUTAMATE.
PSA: 103.86000
LogP: 0.28730
Synthetic route
56-86-0

L-glutamic acid

NH3

NH3

7558-63-6

L-glutamate

56-85-9

L-glutamine

7558-63-6

L-glutamate

Conditions
ConditionsYield
With L-glutamate dehydrogenase at 30℃; for 0.166667h; aq. phosphate buffer;
60-29-7

diethyl ether

7558-63-6

L-glutamate

SOCl2

SOCl2

A

L-glutamic acid-5-anilide

L-glutamic acid-5-anilide

B

(S)-5-oxo-pyrrolidine-carboxylic acid-(2)-anilide

(S)-5-oxo-pyrrolidine-carboxylic acid-(2)-anilide

Conditions
ConditionsYield
Umsetzung des Reaktionsprodukts mit Anilin in Chloroform;
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    7558-63-6

    L-Glutamic acid,ammonium salt (1:1)

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Chemistry

Molecule structure of Monoammonium L-glutamate (CAS NO.7558-63-6) :

IUPAC Name: azanium 4-amino-5-hydroxy-5-oxopentanoate 
Molecular Weight: 164.15978 g/mol
Molecular Formula: C5H12N2O4 
Boiling Point: 438.1 °C at 760 mmHg
Flash Point: 218.8 °C
Enthalpy of Vaporization: 76.19 kJ/mol
Vapour Pressure: 6.69E-09 mmHg at 25 °C 
Storage Temp.: −20 °C
H-Bond Donor: 3
H-Bond Acceptor: 5
Rotatable Bond Count: 3
Exact Mass: 164.079707
MonoIsotopic Mass: 164.079707
Topological Polar Surface Area: 105
Heavy Atom Count: 11
Complexity: 139
Canonical SMILES: C(CC(=O)[O-])C(C(=O)O)N.[NH4+]
InChI: InChI=1S/C5H9NO4.H3N/c6-3(5(9)10)1-2-4(7)8;/h3H,1-2,6H2,(H,7,8)(H,9,10);1H3
InChIKey: PHKGGXPMPXXISP-UHFFFAOYSA-N
EINECS: 231-447-1

Uses

 Monoammonium L-glutamate (CAS NO.7558-63-6) is used as flavoring agent, on behalf of the salts.

Production

 Monoammonium L-glutamate (CAS NO.7558-63-6) is obtained by the fermentation of glutamate and ammonium hydroxide or ammonium carbonate crystallization during and after the bleaching refining.

Toxicity Data With Reference

1.    

ipr-rat LD50:1000 mg/kg

    HSZPAZ    Hoppe-Seylers Zeitschrift fuer Physiologische Chemie. 300 (1955),97.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic fumes including NOx and NH3. See also MONOSODIUM GLUTAMATE.
Hazard Codes: IrritantXi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: MA1400000

Specification

 Monoammonium L-glutamate (CAS NO.7558-63-6) is also called Ammonium glutamate ; Ammoniumglutaminat ; Ammoniumglutaminat [German] ; Glutamic acid, monoammonium salt, L- ; Ammonium L-glutamate ; L-Glutamic acid, ammonium salt (1:1) ; L-Glutamic acid, monoammonium salt . Monoammonium L-glutamate (CAS NO.7558-63-6) is white, almost no smell, easy flow of crystalline powder with a special taste. It is soluble in water and almost insoluble in common organic solvents. The PH of 5% aqueous solution is 6.0 ~ 7.0.