76-06-2

Product Name: Trichloronitromethane  
CAS: 76-06-2
Formula: CCl₃NO₂
Molecular Weight: 164.38
Molecular Structure of Trichloronitromethane (76-06-2):

Density: 1.786 g/cm³ 
Flash Point: 13 °C
Boiling Point: 112 °C at 760 mmHg
Index of Refraction: 1.503 
Molar Refractivity: 27.21 cm³ 
Molar Volume: 92 cm³ 
Polarizability: 10.78×10^-24cm³ 
Surface Tension: 46.9 dyne/cm 
Appearance: oily colourless liquid
Enthalpy of Vaporization: 35.06 kJ/mol  
Vapour Pressure: 22.2 mmHg at 25°C 
Water Solubility: 1.058e+005(mg/L) at 25°C
Product Categories: organics

NCI Carcinogenesis Bioassay (gavage); No Evidence: mouse NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-GC-TR-65 ,1978. . Reported in EPA TSCA Inventory.

cPoison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by inhalation. Human systemic effects by inhalation: lachrymation, conjunctiva irritation, and pulmonary changes. Mutation data reported. A powerful irritant that affects all body surfaces. It causes lachrymation, vomiting, bronchitis, pulmonary edema, irritation to gastrointestinal and respiratory tracts. Questionable carcinogen with experimental tumorigenic data. An additional toxic effect is its reaction with SH-groups in hemoglobin, thus interfering with oxygen transport. Photochemical transformation of chloropicrin into phosgene (carboxy chloride, COCl₂) has been reported. A concentration of 1 ppm causes a smarting pain in the eyes and therefore in itself constitutes a good warning of exposure. Inhalation causes vomiting, probably due to swallowing saliva in which small amounts of chloropicrin have dissolved. Its primary lethal effect is to produce lung injury and it is a difficult gas to protect oneself against because it is chemically inert and does not react with the usual chemicals used in gas masks. Four ppm is sufficient to render a worker unfit for action and 20 ppm, when breathed from 1 to 2 minutes, causes definite bronchial or pulmonary lesions. Industrially it is used as a warning agent in commercial fumigants. It is more toxic than chlorine but less so than phosgene.
Above a critical volume it can be shocked into detonation. Mixtures with 3-bromopropyne are shock- and heat-sensitive explosives. Violent reaction with aniline + heat, alcoholic sodium hydroxide, sodium methoxide, and propargyl bromide. When heated to decomposition it emits very toxic fumes of Cl⁻ and NO_x.
Used for insect and rodent control in grain elevators and bins and as a soil fumigant and fungicide. See also NITRO COMPOUNDS.
Safety Information about Trichloronitromethane (76-06-2):
Hazard Codes: 
T+:
Risk Statements about Trichloronitromethane (76-06-2): 
R22: Harmful if swallowed.
R26:   Very Toxic by inhalation.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements about Trichloronitromethane (76-06-2): 
S36/37: Wear suitable protective clothing and gloves.
S38: In case of insufficient ventilation, wear suitable respiratory equipment.
S45:  case of accident or if you feel unwell, seek medical advice immediately (show label where possible).
RIDADR: UN 1580
RTECS: PB6300000
HazardClass: 6.1(a)
PackingGroup: I

OSHA PEL: TWA 0.1 ppm
ACGIH TLV: TWA 0.1 ppm; Not Classifiable as a Human Carcinogen
DFG MAK: 0.1 ppm (0.68 mg/m³)
DOT Classification:  6.1; Label: Poison (UN 1580); DOT Class: 6.1; Label: Poison, KEEP AWAY FROM FOOD (UN 1583)

  The chemical synonyms of Trichloronitromethane (76-06-2) are 4-01-00-00106 (Beilstein Handbook Reference) ; AI3-00027 ; Acquinite ; BRN 1756135 ; CCRIS 146 ; Caswell No. 214 ; Chloorpikrine ; Chloorpikrine [Dutch] ; Chlor-O-pic ; Chloroform, nitro- ; Chloropicrin ; Chloropicrine ; Chloropicrine [French] ; Chloropicrine [ISO-French] ; Chlorpikrin ; Chlorpikrin [German] ; Cloropicrina ; Cloropicrina [Italian] ; Dojyopicrin ; Dolochlor ; EINECS 200-930-9 ; EPA Pesticide Chemical Code 081501 ; Larvacide 100 ; Methane, trichloronitro- ; Nitrochloroform ; Nitrotrichloromethane ; Nitrotrichloromethane, Trichloronitromethane ;Trichloornitromethaan ; Trichloornitromethaan [Dutch] ; Trichlornitromethan ; Trichlornitromethan [German] ; Trichloronitromethane ; Tricloro-nitro-metano ; Tricloro-nitro-metano [Italian] .Trichloronitromethane mixture is a variable colored liquid usually colorless to yellow. Chloropicrin is noncombustible and the flammability of the mixture will depend on the other component of the mixture. Chloropicrin vapors are heavier than air and Trichloronitromethane is toxic by inhalation.