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765-63-9

Basic Information
CAS No.: 765-63-9
Name: 2,2,3,3-Tetrafluorooxetane
Molecular Structure:
Molecular Structure of 765-63-9 (2,2,3,3-Tetrafluorooxetane)
Formula: C3H2F4O
Molecular Weight: 130.042
Synonyms: 2,2,3,3-TETRAFLUOROOXETANE;2,2,3,3-Tetrafluorooxacyclobutane
Density: 1.482 g/cm3
Boiling Point: -15.774 °C at 760 mmHg
Flash Point: -74.22 °C
PSA: 9.23000
LogP: 1.24470
Synthetic route
116-14-3

polytetrafluoroethylene

765-63-9

2,2,3,3-tetrafluorooxetane

Conditions
ConditionsYield
With paraformaldehyde In hydrogen fluoride
50-00-0

formaldehyd

75-89-8

2,2,2-trifluoroethanol

765-63-9

2,2,3,3-tetrafluorooxetane

Conditions
ConditionsYield
With hydrogen fluoride
116-14-3

polytetrafluoroethylene

50-00-0

formaldehyd

765-63-9

2,2,3,3-tetrafluorooxetane

Conditions
ConditionsYield
With hydrogen fluoride; trifluoroacetic acid at 50℃; under 6600.66 Torr; for 12h; Product distribution / selectivity; autoclave;
With 2,2,3,3,3-pentafluoropropyl trifluoroacetic acid ester; hydrogen fluoride at 50℃; under 6600.66 Torr; for 12h; Product distribution / selectivity; autoclave;
With 2,2,2-trifluoroethyl trifluoroacetate; hydrogen fluoride at 50℃; under 6600.66 Torr; for 12h; Product distribution / selectivity; autoclave;
With hydrogen fluoride at 50℃; under 6600.66 Torr; for 12h; Product distribution / selectivity; autoclave;
765-63-9

2,2,3,3-tetrafluorooxetane

99497-42-4

2,2-difluoro-3-iodopropionyl fluoride

Conditions
ConditionsYield
With sodium iodide94%
With sodium iodide In water
With sodium iodide
6738-06-3

phenylethynylmagnesium bromide

765-63-9

2,2,3,3-tetrafluorooxetane

1319010-93-9

3-bromo-2,2-difluoro-1,1-bis(phenylethynyl)propan-1-ol

Conditions
ConditionsYield
Stage #1: phenylethynylmagnesium bromide; 2,2,3,3-tetrafluorooxetane In tetrahydrofuran at -20 - 20℃; for 20h; Inert atmosphere;
Stage #2: With ammonium chloride In tetrahydrofuran; water
91%
765-63-9

2,2,3,3-tetrafluorooxetane

64-17-5

ethanol

C5H7F2IO2

Conditions
ConditionsYield
With sodium iodide In chloroform at 50℃; for 2h; Solvent; Cooling with ice;90.8%
765-63-9

2,2,3,3-tetrafluorooxetane

64-17-5

ethanol

127-09-3

sodium acetate

380-41-6

ethyl 2,2-difluoro-3-hydroxypropanoate

Conditions
ConditionsYield
Stage #1: 2,2,3,3-tetrafluorooxetane; ethanol; sodium acetate at 45 - 70℃; for 2h; Reflux;
Stage #2: With sulfuric acid for 8h; Reflux;
Stage #3: With sodium hydrogencarbonate In water
81.8%
765-63-9

2,2,3,3-tetrafluorooxetane

60-29-7

diethyl ether

111773-24-1

3-bromo-2,2-difluoropropionic acid ethyl ester

Conditions
ConditionsYield
With magnesium bromide at 0 - 20℃; for 3h; Inert atmosphere;81%
765-63-9

2,2,3,3-tetrafluorooxetane

4039-82-1

Benzyl propargyl ether

1319010-73-5

2,2-difluoro-1,1,3-tris(3-benzyloxyprop-1-ynyl)propan-1-ol

Conditions
ConditionsYield
Stage #1: Benzyl propargyl ether With n-butyllithium In tetrahydrofuran; hexane at -20℃; for 0.25h; Inert atmosphere;
Stage #2: 2,2,3,3-tetrafluorooxetane In tetrahydrofuran; hexane at -20℃; for 2h; Inert atmosphere;
Stage #3: With ammonium chloride In tetrahydrofuran; hexane; water
78%
765-63-9

2,2,3,3-tetrafluorooxetane

100-58-3

phenylmagnesium bromide

1319010-86-0

3-bromo-2,2-difluoro-1,1-diphenylpropan-1-ol

Conditions
ConditionsYield
Stage #1: 2,2,3,3-tetrafluorooxetane; phenylmagnesium bromide In tetrahydrofuran at -20 - 20℃; for 20h; Inert atmosphere;
Stage #2: With ammonium chloride In tetrahydrofuran; water
78%
Downstream Products
111773-24-1
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Specification

The 2, 2, 3, 3-Tetrafluorooxetane has CAS registry number 765-63-9. This chemical's molecular formula is C3H2F4O and molecular weight is 130.041. What's more, its systematic name is 2, 2, 3, 3-Tetrafluorooxetane.

Physical properties about 2, 2, 3, 3-Tetrafluorooxetane are: (1)ACD/LogP: 0.28; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 1; (4)#H bond donors: 0; (5)#Freely Rotating Bonds: 0; (6)Polar Surface Area: 9.23 Å2; (7)Index of Refraction: 1.294; (8)Molar Refractivity: 16.12 cm3; (9)Molar Volume: 87.751 cm3; (10)Polarizability: 6.39×10-24 cm3; (11)Surface Tension: 14.067 dyne/cm; (12)Density: 1.482 g/cm3; (13)Flash Point: -74.22 °C; (14)Enthalpy of Vaporization: 22.612 kJ/mol; (15)Boiling Point: -15.774 °C at 760 mmHg; (16)Vapour Pressure: 3066.063 mmHg at 25 °C.

You can still convert the following datas into molecular structure:
(1) SMILES: FC1(F)COC1(F)F
(2) InChI: InChI=1/C3H2F4O/c4-2(5)1-8-3(2,6)7/h1H2
(3) InChIKey: OFWDLJKVZZRPOX-UHFFFAOYAZ