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Detail of "76584-70-8"

  • CAS Number:
  • 76584-70-8
  • Name:
  • Pentanoic acid, 2-propyl-, sodium salt (2:1)

  • Superlist Name:
  • Divalproex sodium
  • Molecular Structure:
  • Formula:
  • C16H31NaO4
  • Molecular Weight:
  • 310.40
  • Synonyms:
  • Pentanoic acid,2-propyl-, sodium salt (2:1);Abbott50711;Depakote;Epival;Sodium hydrogenbis(2-propylpentanoate);Sodium hydrogen bis(2-propylvalerate);Sodium hydrogendivalproate;Valdisoval;Valproate semisodium;
  • Melting Point:
  • 222 °C
  • Boiling Point:
  • 220 °C at 760 mmHg
  • Flash Point:
  • 116.6 °C

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CAS No.76584-70-8 Divalproex sodium

Assay:98%

Supplier:Taiyuan RHF CO., ltd. [ China (Mainland)]

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CAS No.76584-70-8 Divalproex sodium

Assay:98%

Supplier:Hangzhou Dayangchem Co., Ltd. [ China (Mainland)]

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ISO 3875Integral
3875

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Address:B/2601 Fuli Building, 328# WenEr Rd. Hangzhou City 310012 China

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CAS No.76584-70-8 Divalproex sodium

Supplier:Zouping Mingxing Chemical Co.,Ltd. [ China (Mainland)]

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Manufacturer 2185Integral
2185

Tel:86-543-4350217

Address:428 Daixi Third Road Zouping County Shandong Province China

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CAS No.76584-70-8 Divalproex sodium

Supplier:Jinan Haohua Industry CO., LTD [ China (Mainland)]

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1525Integral
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CAS No.76584-70-8 Divalproex sodium

Supplier:Afine Chemicals Limited [ China (Mainland)]

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930Integral
930

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Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China

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CAS No.76584-70-8 Divalproex sodium

Supplier:Changzhou Highassay Chemical Co., Ltd [ China (Mainland)]

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915Integral
915

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Address:XIXIASHU TOWN, XINBEI DISTRICT, CHANGZHOU, JIANGSU

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CAS No.76584-70-8 Divalproex sodium

Assay:above 98%  Appearance:white crysta...  Package:25kg/fibre d...

Divalproex Sodium

Supplier:Jinan Decheng Hemu Medical Technology Co.,Ltd. [ China (Mainland)]

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1276Integral
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CAS No.76584-70-8 Divalproex sodium

Divalproex Sodium

Supplier:Hangzhou Eastbiopharm Co.,Ltd. [ China (Mainland)]

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1971Integral
1971

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Address:Hangzhou,China

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CAS No.76584-70-8 Divalproex sodium

Supplier:Jiangsu Chiatai Qingjiang Pharmaceutical Co.,Ltd [ China (Mainland)]

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2430

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CAS No.76584-70-8 Divalproex sodium

Supplier:Jewim Pharmaceutical (Shandong) Co., Ltd [ China (Mainland)]

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1377Integral
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CAS No.76584-70-8 Divalproex sodium

Di-valproex sodium Appearance:White powde Melting point:98.0~102.0℃ Heavy metals:≤20ppm Sulfate:≤200ppm Iron:≤50ppm Assay of Valproic acid:45.4~47.4% Assay of Sodium Valproate:52.6~54.6% Assay

Min. Order:100Kilogram

Supplier:Hangzhou Kinsey Bio-tech Co.,Ltd [ China (Mainland)]

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1390Integral
1390

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CAS No.76584-70-8 Divalproex sodium

Divalproate Sodium.99.5%.We're the professional research & develop company, not a trader.We can give the most competitive price.

Supplier:Tianjin Crest Pharmaceutical R&D Co., Ltd. [ China (Mainland)]

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970Integral
970

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Address:Building B5-405, No, 80 4th Avenue, TEDA, Tianjin, China P.R. 300457

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CAS No.76584-70-8 Divalproex sodium

Assay:≥99.0%  Appearance:white crysta...  Package:paper drumStorage:n light-resi...

1.Category : Intermediates/Pharmaceutical intermediates 2.CAS NO : 76584-70-8 3.MF : C16H31NaO4 4.MW : 310.4047 5.Synonyms : divalproex sodium;sodium 2-propylpentanoate 2-propylpentanoic acid (1:1:1);

Min. Order:1Metric Ton

Supplier:Jinan Dingxin Chemical Co.,ltd [ China (Mainland)]

60Integral
60

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Address:room 1109,fortune square,shanghe county, jinan city,shandong province ,china

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CAS No.76584-70-8 Divalproex sodium

Divalproex sodium consists of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form.

Supplier:Selleck Chemicals [ United States]

600Integral
600

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Address:2626 South Loop West, Suite 225, Houston, TX 77054 USA

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CAS No.76584-70-8 Divalproex sodium

Divalproate Sodium

Supplier:Jai Radhe Sales [ India]

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1420

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CAS No.76584-70-8 Divalproex sodium

Divalproex Sodium

Supplier:SINOWAY INTERNATIONAL (JIANGSU) CO., LTD [ China (Mainland)]

660Integral
660

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CAS No.76584-70-8 Divalproex sodium

Divalproex

Supplier:Leawell International Limited [ China (Mainland)]

610Integral
610

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Address:Unit 1002 No. 9 Building 100 Courtyard Xianlie Zhong Rd, Guangzhou China

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CAS No.76584-70-8 Divalproex sodium

Properties Packing: 20/25kg cardboard drum Standard: BP2000 Content: ≥99%

Supplier:YanCheng DongYang Biology Production Co.,Ltd. [ China (Mainland)]

105Integral
105

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Address:8# Shichenlu, Shizhuang Town,Funing County, Jiangsu Province

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CAS No.76584-70-8 Divalproex sodium

Supplier:AZAD FINE CHEMICALS Limited Liability Company [ Switzerland]

215Integral
215

Tel:41 (0)31 810 40 11

Address:Switzerland

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CAS No.76584-70-8 Divalproex sodium

Supplier:Watson International Ltd [ China (Mainland)]

610Integral
610

Tel:+86-512-81867280

Address:Room 1209, Asia Pacific Plaza, Huaqiao International Business Park

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CAS No.76584-70-8 Divalproex sodium

Supplier:JALOR-CHEM CO.,LTD
changzhou Jalor-chem Lab [ China (Mainland)]

600Integral
600

Tel:86-510-8639-6359

Address:Room 524-530,South Building,Chemical Plaza,Science and Education town,Changzhou

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Reference

A pharmaco-economic model of divalproex vs
A pharmaco-economic model of divalproex vs. lithium in the acute and prophylactic treatment of bipolar I disorder. Keck, Paul E., Jr.; Nabulsi, Azmi A.; Taylor, Jennifer L.; Henke, Curtis J.; Chmiel, Joseph J.; Stanton, Sean P.; Bennett, Jerry A. (College Medicine, University Cincinnati, Cincinnati, OH 45267-0559, USA). Journal of Clinical Psychiatry, 57(5), 213-222 (English) 1996 Physicians Postgraduate Press. CODEN: JCLPDE. ISSN: 0160-6689. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Divalproex and lithium are the two most rigorously studied pharmacol. 7439-93-2 and 76584-70-8 are cas registry numbers of chemicals which are used as reagents here. treatments for acute mania in bipolar I disorder in randomized, controlled trials. The differences between the drugs in their time course of onset, predictors of response, and side effects have potentially important pharmacoeconomic implications. Utilizing data from published studies, the University of Cincinnati Mania Project, and a consensus panel of psychiatrists, we developed a decision-analytic model to est. the costs of treating patients with bipolar I disorder, acutely and prophylactically, for 1 yr with divalproex or lithium. In the overall group of patients with bipolar I disorder, initial treatment with divalproex led to costs that were 9% lower than costs for initial treatment with lithium. Cost savings assocd. with divalproex were greatest for patients with mixed mania and rapid cycling, whereas cost savings for patients with classic mania were greater for lithium. According to the decision-analytic model developed in this study, divalproex, possibly because of a more rapid rate of antimanic activity assocd. with oral loading, is a less costly treatment than lithium in the acute and prophylactic treatment of patients with bipolar I disorder over 1 yr. .
Pharmacokinetic interactions and side effects resulting from concomitant administration of lithium and divalproex sodium
Pharmacokinetic interactions and side effects resulting from concomitant administration of lithium and divalproex sodium. Granneman, G. Richard; Schneck, Dennis W.; Cavanaugh, John H.; Witt, Galen F. (Abbott Laboratories, North Chicago, IL 60064-3500, USA). 76584-70-8 and 7439-93-2 are cas registry numbers. These chemicals are also mentioned in this article. Journal of Clinical Psychiatry, 57(5), 204-206 (English) 1996 Physicians Postgraduate Press. CODEN: JCLPDE. ISSN: 0160-6689. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Valproic acid is added to the lithium regimens of many patients with bipolar disorder, esp. those with mania refractory to lithium treatment. We evaluated the pharmacokinetic effects and safety of coadministration of lithium and valproate in 16 healthy volunteers in this randomized, placebo-controlled, two-period (12 days each) crossover trial. Valproate or placebo was given twice daily. On Days 6-10, lithium was added. Blood samples drawn on Days 5 and 10 were analyzed for valproate by high-pressure liq. chromatog. (HPLC) and for lithium by at. absorption spectrophotometry. Lithium pharmacokinetics were unchanged by valproate, but valproate Cmax, Cmin, and AUC rose slightly during lithium coadministration. Adverse events did not change significantly. Concomitant administration of lithium and valproate appears to be safe in patients with bipolar disorder. .
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