Reference

Determination of water-soluble components in Salvia miltiorrhiza injections by thin layer chromatography

Determination of water-soluble components in Salvia miltiorrhiza injections by thin layer chromatography. Ni, Kunyi; Zhang, Yumei; Yu, Rugu (Dep. Anal. Chem., Nanjing Coll. Pharm., Nanjing, Peop. Rep. China). Nanjing Yaoxueyuan Xuebao, 17(4), 265-9 (Chinese) 1986. CODEN: NYXUDF. ISSN: 0254-5055. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Three water-sol. components, Dan Shen Su (I) [76822-21-4], protocatechuic aldehyde (II) [139-85-5] and protocatechuic acid (III) [99-50-3] in Salvia miltiorrhiza injections were chromatographed on a silica gel G plate using CHCl3-EtOAc-C6H6-HCO2H (5:6:3:1) as developing solvent by TLC densitometric scanning. Calibration graphs were linear in the range 4-18 mg for I, 1-8 mg for II and 1-6 mg for III. Nine Salvia miltiorrhiza injections and 3 compds. were analyzed at 280 nm (400 nm as ref. wavelength). The recoveries were 99.6-99.9% and the variation coeffs. were 3-5%. The range of contents (mg/mL) was 4.78-10.2 for I, 0.638-1.32 for II and 0.144-0.261 for III.Except for chemicals metioned above, 99-50-3 and 139-85-5 are also used. .

Effects of sodium b-3,4-dihydroxyphenyllactate and b-phenyllactic acid on PGI2 and TXA2 contents in the plasma of rabbits after coronary artery occlusion

Effects of sodium b-3,4-dihydroxyphenyllactate and b-phenyllactic acid on PGI2 and TXA2 contents in the plasma of rabbits after coronary artery occlusion. Zhu, Liang; Shao, Yide; Dai, Huajuan; Dong, Jichang; Xue, Fen (Sch. Pharm., Shanghai Med. Univ., Shanghai, Peop. Rep. China).Several substances with their cas registry numbers 69339-96-4 and 35121-78-9 may be metioned in this study. Zhongguo Yaoli Xuebao, 7(6), 533-6 (Chinese) 1986. CODEN: CYLPDN. ISSN: 0253-9756. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) In rabbits with myocardial infarction induced by coronary artery occlusion, elevation of S-T segment was inhibited by i.v. injection of (+)-b-3,4-dihydroxyphenyllactic acid [(+)-I] [76822-21-4], from Salvia miltiorrhiza, and (±)-b-phenyllactic acid (II) [828-01-3], but not by synthetic (±)-I [69339-96-4]; the contents of plasma TXA2 [57576-52-0] were decreased by (+)-I, (±)-I, or II and those of plasma PGI2 [35121-78-9] were decreased by (+)- and (±)-I but not by II. .