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7699-19-6

Basic Information
CAS No.: 7699-19-6
Name: 6-Methoxy-2-oxindole
Article Data: 19
Molecular Structure:
Molecular Structure of 7699-19-6 (6-Methoxy-2-oxindole)
Formula: C9H9 N O2
Molecular Weight: 163.176
Synonyms: 2-Indolinone,6-methoxy- (7CI,8CI); 1,3-Dihydro-6-methoxy-2H-indol-2-one;6-Methoxy-1,3-dihydroindol-2-one; 6-Methoxy-2-indolinone; 6-Methoxy-2-oxindole;6-Methoxy-2-oxoindoline; 6-Methoxyoxindole
Density: 1.208 g/cm3
Melting Point: 162 °C
Boiling Point: 342.3 °C at 760 mmHg
Flash Point: 160.8 °C
PSA: 38.33000
LogP: 1.32780
Synthetic route
113519-32-7

1,6-dimethoxyindolin-2-one

7699-19-6

6-methoxyoxindole

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol94%
108274-39-1

ethyl 2-(4-methoxy-2-nitrophenyl)acetate

7699-19-6

6-methoxyoxindole

Conditions
ConditionsYield
With iron In acetic acid at 100℃; for 1h;70%
With iron; acetic acid at 100℃; for 1h;42%
52351-75-4

6-methoxyisatin

7699-19-6

6-methoxyoxindole

Conditions
ConditionsYield
With hydrazine hydrate; potassium hydroxide at 140℃; for 4h;60%
1355049-20-5

methyl {2-[(anilinocarbonyl)amino]-4-methoxyphenyl}acetate

A

7699-19-6

6-methoxyoxindole

B

1355049-23-8

2-hydroxy-6-methoxy-N-phenyl-1H-indole-3-carboxamide

C

1355049-22-7

2-hydroxy-6-methoxy-N1,N3-diphenyl-1H-indole-1,3-dicarboxamide

D

102-07-8

bis(diphenyl)urea

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 60℃;A 26%
B 2.6%
C 56%
D 2.9%
121726-58-7

N-Acetoxy-2-(4-methoxy-phenyl)-acetamide

7699-19-6

6-methoxyoxindole

Conditions
ConditionsYield
With iron(III) chloride; acetic acid In dichloromethane Ambient temperature;50%

3-(4-methoxybenzyl)-1,4,2-dioxazol-5-one

7699-19-6

6-methoxyoxindole

Conditions
ConditionsYield
With chlorido(8-quinolinolato-k2N,O)(η5-pentamethylcyclopentadienyl)iridium(III); sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate at 60℃; for 12h;22%
147124-33-2

dimethyl 2-(4-methoxy-2-nitrophenyl)malonate

7699-19-6

6-methoxyoxindole

Conditions
ConditionsYield
Stage #1: dimethyl 2-(4-methoxy-2-nitrophenyl)malonate With lithium chloride In dimethyl sulfoxide at 100℃; for 3h;
Stage #2: With iron; acetic acid at 100℃; for 1h;
10298-80-3

2-chloro-5-methoxynitrobenzene

7699-19-6

6-methoxyoxindole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: tBuOK / dimethylformamide / 0.17 h / 90 °C
1.2: dimethylformamide / 12 h / 90 °C
2.1: LiCl / dimethylsulfoxide / 3 h / 100 °C
2.2: acetic acid; iron / 1 h / 100 °C
View Scheme
Multi-step reaction with 3 steps
1: 1) NaH / 1) DMSO, 100 deg C, 40 min, 2a) RT, 30 min, 2b) 100 deg C, 1 h
2: 71 percent / LiCl / dimethylsulfoxide; H2O / 3 h / 100 °C
3: 70 percent / Fe powder / acetic acid / 1 h / 100 °C
View Scheme
Multi-step reaction with 3 steps
1.1: sodium hydride / N,N-dimethyl-formamide / 0.67 h / 20 - 100 °C
1.2: 1.5 h / 20 - 100 °C
2.1: water; lithium hydroxide monohydrate / dimethyl sulfoxide / 2 h / 100 °C
3.1: acetic acid; iron / 1 h / 100 °C
View Scheme
10565-15-8

diethyl 2-(4-methoxy-2-nitrophenyl)malonate

7699-19-6

6-methoxyoxindole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 71 percent / LiCl / dimethylsulfoxide; H2O / 3 h / 100 °C
2: 70 percent / Fe powder / acetic acid / 1 h / 100 °C
View Scheme
With iron; acetic acid at 120℃;
Multi-step reaction with 2 steps
1: water; lithium hydroxide monohydrate / dimethyl sulfoxide / 2 h / 100 °C
2: acetic acid; iron / 1 h / 100 °C
View Scheme
2594-06-1

2-(4-methoxyphenyl)acetohydroxamic acid

7699-19-6

6-methoxyoxindole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: 50 percent / FeCl3, CH3COOH / CH2Cl2 / Ambient temperature
View Scheme
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Chemistry

Molecular Structure of 2H-Indol-2-one,1,3-dihydro-6-methoxy- (CAS NO.7699-19-6):

IUPAC Name: 6-methoxy-1,3-dihydroindol-2-one 
CAS: 7699-19-6
Empirical Formula: C9H9NO2
Molecular Weight: 163.1733
H bond acceptors: 3
H bond donors: 1
Freely Rotating Bonds: 1
Polar Surface Area: 29.54 Å2
Index of Refraction: 1.564
Molar Refractivity: 43.97 cm3
Molar Volume: 135 cm3
Surface Tension: 42.3 dyne/cm
Density: 1.208 g/cm3
Flash Point: 160.8 °C
Enthalpy of Vaporization: 58.6 kJ/mol
Boiling Point: 342.3 °C at 760 mmHg
Vapour Pressure: 7.59E-05 mmHg at 25°C
Product Categories: blocks; IndolesOxindoles; Indoline & Oxindole

Specification

  2H-Indol-2-one,1,3-dihydro-6-methoxy- , with CAS number of 7699-19-6, can be called Aurora ka-6734 ; 6-methoxyoxindole ; 6-methoxyindol-2(3h)-one ; 6-methoxy-2-oxyindole ; 6-methoxy-2-indolinone ; 2,3-dihydro-6-methoxy-2h-indol-2-one ; 2h-indole-2-one, 1,3-dihydro-6-methoxy ; 6-methoxyindolin-2-one .