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| CAS No.: | 77-07-6 |
|---|---|
| Name: | levorphanol |
| Article Data: | 28 |
| Molecular Structure: | |
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| Formula: | C17H23 N O |
| Molecular Weight: | 257.376 |
| Synonyms: | 2H-10,4a-Iminoethanophenanthren-6-ol,1,3,4,9,10,10a-hexahydro-11-methyl- (7CI); (-)-3-Hydroxy-N-methylmorphinan;(-)-N-Methylmorphinan-3-ol; Aromarone; Levorphan; Levorphanol;N-Methyl-3-hydroxymorphinan; Ro 1-5431; l-Levorphanol |
| Density: | 1.17g/cm3 |
| Melting Point: | 198-199° |
| Boiling Point: | 410.4°Cat760mmHg |
| Flash Point: | 207.2°C |
| Safety: | Poison by ingestion, subcutaneous, and intravenous routes. Experimental reproductive effects reported. When heated to decomposition it emits toxic fumes of NOx. |
| PSA: | 23.47000 |
| LogP: | 3.01830 |
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This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.
Chemistry
Molecular Structure of Levorphanol (CAS NO.77-07-6):
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IUPAC Name: 4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde
Empirical Formula: C17H23NO
Molecular Weight: 257.3706
Index of Refraction: 1.62
Surface Tension: 52 dyne/cm
Density: 1.17 g/cm3
Flash Point: 207.2 °C
Enthalpy of Vaporization: 68.84 kJ/mol
Boiling Point: 410.4 °C at 760 mmHg
Vapour Pressure: 2.55E-07 mmHg at 25°C
Toxicity Data With Reference
| 1. | orl-rat LD50:150 mg/kg | 27ZIAQ Drug Dosages in Laboratory Animals-A Handbook C.D. Barnes andL.G. Eltherington,Berkeley, CA.: Univ. of California Press,1973,126. | ||
| 2. | scu-rat LD50:110 mg/kg | 27ZIAQ Drug Dosages in Laboratory Animals-A Handbook C.D. Barnes andL.G. Eltherington,Berkeley, CA.: Univ. of California Press,1965. | ||
| 3. | orl-mus LD50:285 mg/kg | 27ZIAQ Drug Dosages in Laboratory Animals-A Handbook C.D. Barnes andL.G. Eltherington,Berkeley, CA.: Univ. of California Press,1973,126. | ||
| 4. | scu-mus LD50:187 mg/kg | 27ZIAQ Drug Dosages in Laboratory Animals-A Handbook C.D. Barnes andL.G. Eltherington,Berkeley, CA.: Univ. of California Press,1965. | ||
| 5. | ivn-mus LD50:41 mg/kg | 27ZIAQ Drug Dosages in Laboratory Animals-A Handbook C.D. Barnes andL.G. Eltherington,Berkeley, CA.: Univ. of California Press,1965. |
Safety Profile
Poison by ingestion, subcutaneous, and intravenous routes. Experimental reproductive effects reported. When heated to decomposition it emits toxic fumes of NOx.
Specification
Levorphanol ,its cas register number is 89111-63-7. It also can be called Morphinan-3-ol,17-methyl-,(-)- .
Levorphanol (CAS NO.77-07-6) is an opioid medication used to treat severe pain. It is the laevorotary stereoisomer of the synthetic morphinan (Dromoran) and a pure opioid agonist.