Detail of "77-83-8"

CAS Number:
77-83-8
Name:
2-Oxiranecarboxylicacid, 3-methyl-3-phenyl-, ethyl ester
Superlist Name:
Ethyl 3-methyl-3-phenylglycidate
Molecular Structure:
Formula:
C₁₂H₁₄O₃
Molecular Weight:
206.26
Synonyms:
Hydrocinnamicacid, a,b-epoxy-b-methyl-, ethyl ester (7CI,8CI);Oxiranecarboxylic acid, 3-methyl-3-phenyl-,ethyl ester (9CI);3-Methyl-3-phenylglycidic acid ethyl ester;Aldehyde C16;Ethyl methylphenylglycidate;Ethyl a,b-epoxy-b-methylhydrocinnamate;Fraeseol;NSC 27905;Strawberry aldehyde;
EINECS:
201-061-8
Density:
1.139 g/cm³
Boiling Point:
273.5 °C at 760 mmHg
Flash Point:
109.4 °C
Appearance:
clear yellow liquid
Hazard Symbols:
Xi
Risk Codes:
10-36/37/38
Safety:
16-26-36/37/39 Details
Transport Information:
UN 1993 3/PG 3

Study of artificial flavoring substances for mutagenicity in the Salmonella/microsome, Basc and micronucleus tests: Study of artificial flavoring substances for mutagenicity in the Salmonella/microsome, Basc and micronucleus tests. Wild, D.; King, M. T.In this study， 91-62-3 and 104-45-0 are also used.; Gocke, E.; Eckhardt, K. (Zentrallab. Mutagenitaetspruef., Dtsch. Forschungsgemeinsch., Freibrug D-7800, Fed. Rep. Ger.). Food Chem. Toxicol., 21(6), 707-19 (English) 1983. CODEN: FCTOD7. ISSN: 0278-6915. DOCUMENT TYPE: Journal CA Section: 17 (Food and Feed Chemistry) Seventy-six compds. used as artificial flavoring substances in food products were studied for mutagenic properties by the use of the Salmonella/mammalian microsome test (Ames test), Basc test on Drosophilia melanogaster, and micronucleus test on mouse bone marrow. The following 4 compds. were mutagenic in Ames tests. EtNO2 [109-95-5], ethyl 3-phenylglycidate [121-39-1], 6-methylquinoline [91-62-3] and musk ambrette. Of these EtNO2 and musk ambrette also induced an increase in sex-linked recessive lethal mutations in Drosophila. Two further compds. ethyl 3-methyl-3-phenylglycidate [77-83-8] and 4-propylanisole [104-45-0], appeared weakly mutagenic in Drosophila only. The result with 4-propylanisole was of equivocal biol. significance. None of the flavoring substances induced micronuclei, i.e. cytogenetic damage in the bone marrow of mice. .

Analytical identification of aldehyde C16 by mass spectrometry combined with gas chromatography, proton-NMR and carbon-13-NMR spectrometry: Analytical identification of aldehyde C16 by mass spectrometry combined with gas chromatography, proton-NMR and carbon-13-NMR spectrometry. Deki, Mitsuo; Yoshimura, Minoru (Cent. Customs Lab., Minist. Finance, Matsudo, Japan). Kanzei Chuo Bunsekishoho, 16, 29-35 (Japanese) 1976. CODEN: KCBSDI. DOCUMENT TYPE: Journal CA Section: 17 (Foods) Combined mass spectrometry and gas chromatog. were used for the anal. of minor components of Aldehyde C16 [77-83-8]. Most of the minor components were identified. These include acetophenone, cinnamyl butenoate, Me cinnamate, methylphenylglycidate and ethylphenylglycidate. Acetophenone is an impurity from the synthetic process of Aldehyde C16, but methylphenylglycidate and ethylphenylglycidate are flavor additives. Mass fragmentation, H1-NMR, and C13-NMR spectra of ethyl-3-methyl-3-phenylglycidate [19464-95-0], which is the main component of Aldehyde C16, were also discussed.