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77614-16-5

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Basic Information
CAS No.: 77614-16-5
Name: DERMORPHIN ACETATE
Article Data: 3
Molecular Structure:
Molecular Structure of 77614-16-5 (DERMORPHIN ACETATE)
Formula: C40H50N8O10
Molecular Weight: 802.885
Synonyms: H-Tyr-D-ala-phe-gly-tyr-pro-ser-NH2;Tyrosyl-alanyl-phenylalanyl-glycyl-tyrosyl-prolyl-serinamide;Dermorphin;
Density: 1.363g/cm3
Melting Point: 157-159 °C
Boiling Point: 1323.8°C at 760 mmHg
Flash Point: 754.4°C
PSA: 314.05000
LogP: 3.98630
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Synthetic route

Z-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2

77614-16-5

dermorphin

Conditions
ConditionsYield
With formic acid; palladium80%
4530-20-5

BOC-glycine

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1-(tert-butoxycarbonyl)-L-proline

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O-benzyl-N-tert-butoxycarbonyl-L-tyrosine

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BOC-O-benzyl-L-serine

Boc-Phe-OH, Boc-D-Ala-OH

Boc-Phe-OH, Boc-D-Ala-OH

77614-16-5

dermorphin

Conditions
ConditionsYield
Yield given. Multistep reaction;
...Expand
29022-11-5

N-(fluoren-9-ylmethoxycarbonyl)glycine

71989-31-6

Fmoc-Pro-OH

35661-40-6

N-Fmoc L-Phe

71989-33-8

Fmoc-Ser(tBu)-OH

71989-38-3

Fmoc-Tyr(tBu)-OH

35661-38-2, 35661-39-3, 79990-15-1

N-(9-fluorenylmethoxycarbonyl)-D-alanine

77614-16-5

dermorphin

Conditions
ConditionsYield
Stage #1: Fmoc-Ser(tBu)-OH With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine In 1-methyl-pyrrolidin-2-one; N,N-dimethyl-formamide at 20℃; for 1h;
Stage #2: With piperidine In 1-methyl-pyrrolidin-2-one for 0.333333h;
Stage #3: N-(fluoren-9-ylmethoxycarbonyl)glycine; Fmoc-Pro-OH; N-Fmoc L-Phe; Fmoc-Tyr(tBu)-OH; N-(9-fluorenylmethoxycarbonyl)-D-alanine Further stages;
...Expand
77614-16-5

dermorphin

830-03-5

4-nitrophenol acetate

86129-31-9

N-Acetyl-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 0℃; for 12h;76%
77614-16-5

dermorphin

1-[2-[2-(2-{2-[2-amino-3-(4-hydroxy-3,5-diiodo-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-3,5-diiodo-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide

Conditions
ConditionsYield
With [bis(pyridine)iodine]+ tetrafluoroborate In dichloromethane at 20℃; for 0.166667h; Iodination;
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    Appearance:white to off-white powder Storage:-20°C Package:according to contract Application:Dermorphin is a natural heptapeptide mu-opioid receptor (MOR) agonist found in amphibian skin. dermorphin is used to inhibit neuralgia. Transportation:Deve

    shuoKang biotechnology co., LTD. Is located in wuhan, China,is mainly engaged in fine chemicals and pharmaceutical intermediates, always adhere to the "market-oriented, based on qu

  • Wuhan Shuokang Biological Technology Co.，Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86 027-87366298

    Address:wuhan

       Inquiry Now

  • dermorphin acetate

  • Casno:

    77614-16-5

    dermorphin acetate

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    We have strong R&D center which can support and provide custom synthesis accordingly such as fine chemicals,biotechnique , pharmaceuticals etc.We can provide free sample for our clients to test anf verify the quality of our goods.LongyuChem holds str

    Shanghai Longyu biotech Co., Ltd. is a large-scale modern chemical production enterprise dedicated to the production, research and development and sales of chemical products. It co

  • shanghai Longyu biotechnology Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-15821988213

    Address:Dalian Rd 950th

       Inquiry Now

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