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Detail of "777-44-6"

  • CAS Number:
  • 777-44-6
  • Name:

  • 3-(Trifluoromethyl)benzenesulfonyl chloride

  • Molecular Structure:
  • Formula:
  • C7H4ClF3O2S
  • Molecular Weight:
  • 244.61
  • Synonyms:
  • 3-(Trifluoromethyl)Benzylsulfonyl Chloride;3-trifluoromethylbenzenesulfonyl chloride;
  • Density:
  • 1.532 g/cm3
  • Boiling Point:
  • 261.1 °C at 760 mmHg
  • Flash Point:
  • 111.7 °C
  • Appearance:
  • clear pale yellow to brown liquid
  • Hazard Symbols:
  • CorrosiveC
  • Risk Codes:
  • 34
  • Safety:
  • 26-36/37/39-45-25 Details
  • Transport Information:
  • UN 3265 8/PG 2
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CAS No.777-44-6 3-(Trifluoromethyl)benzenesulfonyl chlorideCompetitive Product

Assay:98%  Appearance:clear pale y...  Package:On requireme...

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CAS No.777-44-6 3-(Trifluoromethyl)benzenesulfonyl chlorideCompetitive Product

3-(Trifluoromethyl)benzenesulfonyl chloride

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CAS No.777-44-6 3-(Trifluoromethyl)benzenesulfonyl chloride

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CAS No.777-44-6 3-(Trifluoromethyl)benzenesulfonyl chloride

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CAS No.777-44-6 3-(Trifluoromethyl)benzenesulfonyl chloride

777-44-6 3-(Trifluoromethyl)benzenesulfonyl chloride Name 3-(Trifluoromethyl)benzenesulfonyl chloride Synonyms 3-(Trifluoromethyl)benzene-1-sulfonyl chloride Molecular Formula C7H4ClF3O2S Molecular Weight 244.61 CAS Registry Number 777-44-6 Density 1.5

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CAS No.777-44-6 3-(Trifluoromethyl)benzenesulfonyl chloride

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CAS No.777-44-6 3-(Trifluoromethyl)benzenesulfonyl chloride

3-(trifluoromethyl)benzene sulfonyl chloride

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CAS No.777-44-6 3-(Trifluoromethyl)benzenesulfonyl chloride

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CAS No.777-44-6 3-(Trifluoromethyl)benzenesulfonyl chloride

3-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE

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CAS No.777-44-6 3-(Trifluoromethyl)benzenesulfonyl chloride

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CAS No.777-44-6 3-(Trifluoromethyl)benzenesulfonyl chloride

5-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE

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CAS No.777-44-6 3-(Trifluoromethyl)benzenesulfonyl chloride

5-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE

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Reference

2-Thioxo-oxazolidine inhibitors of phosphatidylinositol 3-kinase and their use in treatment of cancer, inflammation, and immune diseases
2-Thioxo-oxazolidine inhibitors of phosphatidylinositol 3-kinase and their use in treatment of cancer, inflammation, and immune diseases. Drees, Beth E.; Chakravarty, Leena; Prestwich, Glenn D.; Dorman, Gyorgy; Kavecz, Mariann; Lukacs, Andras; Urge, Laszlo; Darvas, Ferenc (Echelon Biosciences Incorporated; Comgenex, Rt., USA). PCT Int. Appl. WO 2005002514 A2 13 Jan 2005, 58 pp. DESIGNATED STATES: W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW; RW: AT, BE, BF, BJ, CF, CG, CH, CI, CM, CY, DE, DK, ES, FI, FR, GA, GB, GR, IE, IT, LU, MC, ML, MR, NE, NL, PT, SE, SN, TD, TG, TR. (English). (World Intellectual Property Organization). CODEN: PIXXD2. CLASS: ICM: A61K. APPLICATION: WO 2004-US19131 14 Jun 2004. PRIORITY: US 2003-PV478165 13 Jun 2003. DOCUMENT TYPE: Patent CA Section: 7 (Enzymes) Section cross-reference(s): 1 2-Thioxo-oxazolidine compds. inhibiting phosphatidylinositol 3-kinase (PI 3-K) activities and methods of their use in treating diseases are disclosed. Compds. inhibiting PI 3-K activity and methods of using PI 3-K inhibitory compds. to inhibit cancer cell growth or to treat disorders of immunity and inflammation, in which PI 3-K plays a role in leukocyte function are also provided. Thus, the synthesis of two PI 3-K inhibitors is presented. 777-44-6 and 821775-02-4 are just another two chemicals used in this study. Compds. of this type are shown to inhibit cancer cell growth in vitro and in vivo. .
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