Products Categories
| CAS No.: | 77771-02-9 |
|---|---|
| Name: | 3-Bromo-4-fluorobenzaldehyde |
| Article Data: | 15 |
| Molecular Structure: | |
|
|
|
| Formula: | C7H4BrFO |
| Molecular Weight: | 203.011 |
| Synonyms: | Benzaldehyde, 3-bromo-4-fluoro-;4--bromo-3-fluorobenzaldehyde;4-Fluoro-3-bromobenzaldehyde;3-bromo-4-fluoro-benzaldehyde;4-fluoro-3- bromobenzaldehyde; |
| EINECS: | 278-764-1 |
| Density: | 1.67 g/cm3 |
| Melting Point: | 28-33 °C |
| Boiling Point: | 311.9 °C at 760 mmHg |
| Flash Point: | 99 °C |
| Solubility: | INSOLUBLE |
| Appearance: | white to light yellow low melting solid |
| Hazard Symbols: |
 Xi,  Xn
|
| Risk Codes: | 22-36/37/38 |
| Safety: | 26-36-37/39 |
| PSA: | 17.07000 |
| LogP: | 2.40070 |
- 81281-59-67-Benzylideneaminotheophylline
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 852475-26-4MC1568
- 958254-66-51H-Imidazo[4,5-b]pyridine-2-carboxaldehyde, 1-methyl-, hydrochloride
- 99170-93-1N-Methyl-2-oxazolamine
- 914458-26-7[5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-Methanone
- 894852-01-87-BROMO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
- 90221-55-92-bromo-5-methylbenzaldehyde
- 885590-99-82,3-DIFLUORO-4-IODOBENZALDEHYDE
- 97730-31-9(S)-4'-(2-Methylbutyl)Biphenyl-4-Carbonitrile
- 459-57-4
4-fluorobenzaldehyde
- 77771-02-9
3-bromo-4-fluorobenzaldehyde
| Conditions | Yield |
|---|---|
| With sulfuric acid; sulfur trioxide; bromine; iodine; zinc dibromide at 30 - 40℃; for 5.91667h; Product distribution / selectivity; Inert atmosphere; | 97% |
| With hydrogenchloride; sodium hypochlorite solution; sodium bromide In dichloromethane; water at 20 - 25℃; for 1.5h; Irradiation; | 91.9% |
| With bromine; aluminium trichloride In dichloromethane |
- 77771-03-0
3-bromo-4-fluoro-benzyl alcohol
- 77771-02-9
3-bromo-4-fluorobenzaldehyde
| Conditions | Yield |
|---|---|
| With dipotassium peroxodisulfate at 55℃; for 0.25h; Ionic liquid; | 87% |
| With pyridine; hydrogenchloride In dichloromethane | |
| With potassium dichromate; sulfuric acid In dichloromethane; water | |
| With sodium hydroxide; nitric acid In water; toluene |
- 2973-78-6
3-bromo-4-hydroxybenzylaldehyde
- 77771-02-9
3-bromo-4-fluorobenzaldehyde
| Conditions | Yield |
|---|---|
| With Cl(1-)*C27H36ClN2(1+)*Cs(1+)*F(1-) In toluene at 23 - 110℃; for 24h; Inert atmosphere; | 61% |
- 701914-09-2
2-bromo-1-fluoro-4-vinyl-benzene
B
- 77771-02-9
3-bromo-4-fluorobenzaldehyde
| Conditions | Yield |
|---|---|
| With trimethylsilylazide; oxygen; copper(II) bis(trifluoromethanesulfonate) at 20℃; for 18h; Overall yield = 75 %Spectr.; | A 54% B n/a |
| Conditions | Yield |
|---|---|
| With bromine; aluminium trichloride |
- 77771-02-9
3-bromo-4-fluorobenzaldehyde
- 1007-16-5
3-bromo-4-fluorobenzoic acid
| Conditions | Yield |
|---|---|
| With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene In tetrahydrofuran; water; tert-butyl alcohol at 20℃; for 3h; | 100% |
| With oxygen; Langlois reagent In acetonitrile at 25℃; under 760.051 Torr; for 12h; Irradiation; Green chemistry; | 96% |
| With sodium chlorite In tetrahydrofuran; water at 50℃; for 5h; | 91% |
| Conditions | Yield |
|---|---|
| Stage #1: copper(l) cyanide; 3-bromo-4-fluorobenzaldehyde In 1-methyl-pyrrolidin-2-one at 170℃; for 24h; Stage #2: With celite In 1-methyl-pyrrolidin-2-one at 80℃; for 1h; | 100% |
| In 1-methyl-pyrrolidin-2-one at 170℃; for 24h; | 100% |
| In 1-methyl-pyrrolidin-2-one at 170℃; | 65.4% |
| In 1-methyl-pyrrolidin-2-one at 170℃; for 24h; | 52% |
| In 1-methyl-pyrrolidin-2-one at 25 - 170℃; |
- 77771-02-9
3-bromo-4-fluorobenzaldehyde
- 22483-09-6
2,2-dimethoxyethylamine
- 1036712-61-4
N-[(3-bromo-4-fluoro-phenyl)methyl]-2,2-dimethoxy-ethanamine
| Conditions | Yield |
|---|---|
| Stage #1: 3-bromo-4-fluorobenzaldehyde; 2,2-dimethoxyethylamine In toluene at 20℃; Inert atmosphere; Stage #2: With sodium tetrahydroborate In methanol at 20℃; for 2h; Inert atmosphere; | 100% |
- 5977-14-0
acetoacetamido
- 77771-02-9
3-bromo-4-fluorobenzaldehyde
- 464192-73-2
6-(3-bromo-4-fluorophenyl)-5-cyano-3,6-dihydro-4-methyl-2-oxo-(2H)-pyrimidine
| Conditions | Yield |
|---|---|
| With urea | 99% |
| Conditions | Yield |
|---|---|
| With C23H3BF16N2O In toluene at 25℃; for 3h; Green chemistry; | 99% |
What can I do for you?
Get Best Price
Specification
The 3-Bromo-4-Fluoro benzaldehyde, with its CAS registry number 77771-02-9, is a kind of white to light yellow low melting solid. For being sensitive to air, its product categories are including Fluorin-contained benzaldehyde series; Fluorobenzene; Aromatic Aldehydes & Derivatives (substituted); Benzaldehyde; Miscellaneous; Adehydes, Acetals & Ketones; Bromine Compounds; Fluorine Compounds; Aldehydes; C7; Carbonyl Compounds; Benzaldehyde series.
The physical properties of this chemical are as below: (1)ACD/LogP: 2.30; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.3; (4)ACD/LogD (pH 7.4): 2.3; (5)ACD/BCF (pH 5.5): 32.76; (6)ACD/BCF (pH 7.4): 32.76; (7)ACD/KOC (pH 5.5): 422.92; (8)ACD/KOC (pH 7.4): 422.92; (9)#H bond acceptors: 1; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 17.07 ; (13)Index of Refraction: 1.584; (14)Molar Refractivity: 40.68 cm3; (15)Molar Volume: 121.4 cm3; (16)Polarizability: 16.13×10-24 cm3; (17)Surface Tension: 42.3 dyne/cm; (18)Density: 1.67 g/cm3; (19)Flash Point: 99 °C; (20)Enthalpy of Vaporization: 55.29 kJ/mol; (21)Boiling Point: 311.9 °C at 760 mmHg; (22)Vapour Pressure: 0.000546 mmHg at 25°C; (23)Exact Mass: 201.942956; (24)MonoIsotopic Mass: 201.942956; (25)Topological Polar Surface Area: 17.1; (26)Heavy Atom Count: 10; (27)Complexity: 129.
Use of this chemical: 3-Bromo-4-Fluoro benzaldehyde could react with hexa-Si-methyl-Si,Si'-ethane-1,2-diyldioxy-bis-silane to produce 2-(3-bromo-4-fluoro-phenyl)-[1,3]dioxolane. This reaction could happen in the presence of the reagent of CF3SO3Si(CH3)3, solvent of CH2Cl2. And it needs the reaction time of 1 hour(s) and the reaction temp. of -78 ℃.
.jpg)
When you are dealing with this chemical, you should be very careful. For one thing, it is irritating to eyes, respiratory system and skin and may cause inflammation to the skin or other mucous membranes. For another thing, it is harmful which may cause damage to health, and it will be harmful if swallowed. Therefore, you should wear suitable protective clothing, gloves and eye/face protection, and if in case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
In addition, you could convert the following datas into the molecular structure:
(1)Canonical SMILES: C1=CC(=C(C=C1C=O)Br)F
(2)InChI: InChI=1S/C7H4BrFO/c8-6-3-5(4-10)1-2-7(6)9/h1-4H
(3)InChIKey: FAHZIKXYYRGSHF-UHFFFAOYSA-N