7778-50-9

IARC Cancer Review: Human Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 23 ,1980,p. 205.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 23 ,1980,p. 205.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Chromium and its compounds are on the Community Right-To-Know List. Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

OSHA PEL: CL 0.1 mg(CrO₃)/m³
ACGIH TLV: TWA 0.05 mg(CrO₃)/m³
NIOSH REL: TWA (Chromium(VI)) 0.025 mg(Cr(VI))/m³; CL 0.05/15M

For occupational chemical analysis use NIOSH: Chromium Hexavalent, 7024.

The Potassium bichromate , with the CAS register number 7778-50-9, has other names as bichromateofpotash;chromicaci (h2cr2o7),dipotassiumsalt;chromicacid,dipotassiumsalt;chromicacid[h2cr2o7],dipotassiumsalt;dichromatedepotassium;Dichromicacid,dipotassiumsalt;dichromicacid[h2cr2o7],dipotassiumsalt;dichromicaciddipotassiumsalt .

It is a kind of orange red monoclinic system or triclinic system crystalline, and it is slightly soluble in water and easily soluble in hot water while insoluble in ethyl alcohol .

As for its usage, it is widely used in many field. First, it could be used as the chrome alum, chromium oxide green, chrome yellow pigment. Then, it could be mixed with the  feldspar powder and quartz sand to calcine and then comes enamel powder; It is used in modulating the match head to take the function of anti-moisture; It could be applied to as the tanning extracts and mordant in dyeing and printing; It could be used in making spice to be as oxidant. Besides, it is applied in welding rod, printing ink,passivation of metals and also as the oxidant and catalyst for organic synthesis and the raw material of the medicines.

It is a kind of very harmful chemical and you need to very cautious while dealing with it. Because it is dangerous for the environment, and it is toxic and oxidizing. Besides, it may cause cancer, heritable genetic damage, and impair fertility and it may cause harm to the unborn child, and etc. So take these instructions while using it. Wash hands, face, forearms and neck when exiting restricted areas; Wash hands before eating and do not eat, drink, or smoke in workplace; Wear special protective equipment for maintenance break-in or where exposures may exceed established exposure levels. Shower, dispose of outer clothing, change to clean garments at the end of the day; Protect against physical damage; Remove and dispose of any spilled dichromates; do not return to original containers;

When it comes to its storing, containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product; Store in a dry location separate from combustible, organic or other readily oxidizable materials. Avoid storage on wood floors.

What's more, its product categories are including the followings: inorganics;chromatesvolumetric solutions;n - r;oxidation;salt solutions;synthetic reagents;n - rvolumetric solutions;reference material sodium thiosolfatetitration;salt solutionsanalytical reagents;by reference material;solution containers (volpac);volumetric solutions;waste water;water test;reference material sodium thiosolfate;chromatesconcentrates (e.g. fixanal);concentrates (e.g. fixanal);reference material sodium thiosulfatetitration;salt concentrates.

Below are the toxicity information of this kind of chemcial:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
child	LDLo	oral	26mg/kg (26mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION GASTROINTESTINAL: NAUSEA OR VOMITING	Zeitschrift fuer Kinderheilkunde. Vol. 81, Pg. 417, 1958.
child	LDLo	oral	50mg/kg (50mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 40, Pg. 2677, 1998.
dog	LDLo	oral	2829mg/kg (2829mg/kg)		Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
dog	LDLo	unreported	2300ug/kg (2.3mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 27(12), Pg. 77, 1962.
guinea pig	LDLo	oral	163mg/kg (163mg/kg)		Zeitschrift fuer Kinderheilkunde. Vol. 81, Pg. 417, 1958.
guinea pig	LDLo	subcutaneous	29400ug/kg (29.4mg/kg)		Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
man	LDLo	oral	143mg/kg (143mg/kg)	VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: DYSPNEA KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 40, Pg. 2677, 1998.
monkey	LDLo	subcutaneous	40mg/kg (40mg/kg)	KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"	American Journal of Pathology. Vol. 9, Pg. 133, 1933.
mouse	LD50	intraperitoneal	37mg/kg (37mg/kg)		Carcinogenesis Vol. 4, Pg. 1535, 1983.
mouse	LD50	oral	190mg/kg (190mg/kg)		Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 20, Pg. 590, 1978.
mouse	LDLo	subcutaneous	100mg/kg (100mg/kg)		Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rabbit	LD50	skin	14mg/kg (14mg/kg)	LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	National Technical Information Service. Vol. OTS0537040,
rabbit	LDLo	intravenous	27900ug/kg (27.9mg/kg)		Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rabbit	LDLo	subcutaneous	10mg/kg (10mg/kg)	KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS	Proceedings of the Society for Experimental Biology and Medicine. Vol. 9, Pg. 13, 1911.
rat	LD50	intraperitoneal	28mg/kg (28mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. (5), Pg. 30, 1997.
rat	LD50	oral	25mg/kg (25mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA	National Technical Information Service. Vol. OTS0545929,