Detail of "7789-12-0"

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CAS Number:
7789-12-0
Name:
Sodium dichromate dihydrate
Molecular Structure:
Formula:
Cr₂H₄Na₂O₉
Molecular Weight:
298.02
Synonyms:
Chromicacid (H2Cr2O7), disodium salt, dihydrate (9CI);Dichromic acid (H2Cr2O7),disodium salt, dihydrate (8CI);Dichromic acid, disodium salt, dihydrate;Disodium dichromate dihydrate;Sodium chromate (Na2Cr2O7) dihydrate;Sodiumdichromate (Na2Cr2O7) dihydrate;Chromic acid (H2Cr2O7),sodium salt, hydrate (1:2:2);Sodium dichromatedihydrate (Na2Cr2O7.2H2O);
EINECS:
234-190-3
Density:
2.348 g/cm³
Melting Point:
91 °C(lit.)
Boiling Point:
400 °C
Solubility:
730 g/L (20 °C) in water
Appearance:
orange crystals or needles
Hazard Symbols:
O, T+, N
Risk Codes:
45-46-60-61-8-21-25-26-34-42/43-48/23-50/53
Safety:
53-45-60-61 Details
Transport Information:
UN 3086 6.1/PG 1

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Oral chromium(VI) does not affect the frequency of micronuclei in hematopoietic cells of adult mice and of transplacentally exposed fetuses: All Rights Reserved. Oral chromium(VI) does not affect the frequency of micronuclei in hematopoietic cells of adult mice and of transplacentally exposed fetuses.Several substances are used for example 7789-12-0 and 7778-50-9 which are their cas registry numbers. De Flora, Silvio; Iltcheva, Marietta; Balansky, Roumen M. (Department of Health Sciences, University of Genoa, Genoa I-16132, Italy). Mutation Research, Genetic Toxicology and Environmental Mutagenesis, 610(1-2), 38-47 (English) 2006 Elsevier B.V. CODEN: MRGMFI. ISSN: 1383-5718. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Chromium(VI) compds. are genotoxic in a variety of cellular systems. Their potential carcinogenicity is affected by toxicokinetic patterns restricting bioavailability to certain targets, and by metabolic pathways affecting interaction of chromate-derived reactive species with DNA. Epidemiol. data indicate that chromium(VI) can be carcinogenic to the human respiratory tract following inhalation at doses that are only achieved in certain occupational settings. However, concern has been raised that adverse effects may also result from oral intake. In order to further explore this issue, the authors performed studies in BDF1 and Swiss mice of both genders and various age. Sodium dichromate dihydrate and potassium dichromate were administered either with the drinking water, up to a concn. of 500 mg chromium(VI)/L for up to 210 consecutive days, or in a single intragastric dose of 17.7 mg/kg body wt. Under these conditions, no increase of the micronucleus frequency was obsd. in either bone marrow or peripheral blood erythrocytes. Conversely, the same compds. induced a clastogenic damage following i.p. injection, which by-passes detoxification mechanisms. In addn., due to the hypothesis that susceptibility may be increased during the period of embryogenesis, the authors treated pregnant mice, up to a concn. of 10 mg chromium(VI)/L drinking water. There was no effect on the nos. of fetuses/dam and on body wt. of fetuses. Again, no toxic or genotoxic effect was obsd. either in bone marrow of pregnant mice or in liver and peripheral blood of their fetuses. Thus, even at doses that largely exceed drinking water stds. (up to 10,000 times) or by massive intragastric administration, chromium(VI) is not genotoxic to hematopoietic cells of either adult mice or transplacentally exposed fetuses. These conclusions are consistent with the poor toxicity and lack of carcinogenicity of oral chromium(VI), and are mechanistically explained by the high efficiency of chromium(VI) detoxification processes in the gastrointestinal tract. .

Certain features of the conversion of monochromate alkalies by electrolysis with inert diaphragms: Certain features of the conversion of monochromate alkalies by electrolysis with inert diaphragms. Letskikh, E. S.; Moroz, V. G.; Lyashenko, A. Z.; Karnaev, N. A.; Ryabin, V. A. (USSR). Tr. Ural'sk. N.-i. Khim. In-ta, (37), 52-6 From: Ref. Zh., Metall. 1977, Abstr. 7789-12-0 and 7738-94-5 which are cas registry numbers of substances are two of reagents here. No. 1G298(Russian) 1976. DOCUMENT TYPE: Journal CA Section: 72 (Electrochemistry) Title only translated. .

Detail of "7789-12-0"

Sodium dichromate dihydrate

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Reference