Reference

A synergistic composition for the treatment of diabetes mellitus

A synergistic composition for the treatment of diabetes mellitus. Bhaskaran, Sunil; Mohan, Vishwaraman (Indus Biotech Pvt. Ltd., India). PCT Int.Chemicals with cas numbers 67-63-0 and 781658-23-9 also play role. Appl. WO 2004100968 A2 25 Nov 2004, 27 pp. DESIGNATED STATES: W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW; RW: AT, BE, BF, BJ, CF, CG, CH, CI, CM, CY, DE, DK, ES, FI, FR, GA, GB, GR, IE, IT, LU, MC, ML, MR, NE, NL, PT, SE, SN, TD, TG, TR. (English). (World Intellectual Property Organization). CODEN: PIXXD2. CLASS: ICM: A61K035-78. APPLICATION: WO 2004-IB1550 13 May 2004. PRIORITY: US 2003-PV470742 14 May 2003. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 1 The present invention relates to a synergistic compn. for the treatment of diabetes in a subject in need thereof, comprising trigonelline at concn. of 20 to 30%, amino acids at concn. of 20 to 60%, and sol. fiber at concn. of 10 to 60%, optionally along with pharmaceutically acceptable additives, a process thereof and also, a method of treating diabetes. For example, capsules of a fenugreek seed ext. contg. 20 to 60% amino acids, 20 to 30% of trigonelline, and 10 to 60% galactomannan fiber showed antidiabetic activity in lab. animals and in patients with Type II diabetes mellitus, acting at the pancreas through potassium channel-mediated insulin secretion. .

Use of an amino acid as an inductive agent for the synthesis of SIRT proteins in skin cells

All Rights Reserved. Use of an amino acid as an inductive agent for the synthesis of SIRT proteins in skin cells. Dal Farra, Claude; Domloge, Nouha; Peyronel, Dominique (Societe d'Extraction des Principes Actifs, Fr.). Fr. Demande FR 2887773 A1 5 Jan 2007, 18pp. (French). (France). 438496-81-2 and 781658-23-9 are cas registry numbers of chemicals which are used as reagents here. CODEN: FRXXBL. APPLICATION: FR 2005-7043 1 Jul 2005. DOCUMENT TYPE: Patent CA Section: 62 (Essential Oils and Cosmetics) Section cross-reference(s): 63 The present invention has as an aim the use of at least one isoleucine, mono or polyhydroxylated, and/or one of these derivs., as an inductive active agent of the endogenous synthesis of SIRT proteins in the cells of the skin, or for the prepn. of a cosmetic or pharmaceutical compn. .