Detail of "784-71-4"

Supplier Location
Supplier Location
- China (Mainland)(17)
- United States(2)
- Germany(1)
Business Type
Business Type
- Lab/Research institutions(2)
- Manufacturers(2)
- Trading Company(15)
Certificates
Certificates
- ISO(1)
- Production License (0)

Display：

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Reactions of 2'-deoxy-2'-halouridines and O2,2'-cyclouridine with lithium dialkylamides: formation of 1',2'-unsaturated derivatives: Reactions of 2'-deoxy-2'-halouridines and O2,2'-cyclouridine with lithium dialkylamides: formation of 1',2'-unsaturated derivatives. Kittaka, Atsushi; Tanaka, Hiromichi; Miyasaka, Tadashi; Yamaguchi, Kentaro (Sch. Pharm. Sci., Showa Univ., Tokyo 142, Japan). Nucleosides Nucleotides, 11(1), 37-47 (English) 1992. CODEN: NUNUD5. ISSN: 0732-8311. DOCUMENT TYPE: Journal CA Section: 33 (Carbohydrates) Treatment of 2'-deoxy-2'-halouridine derivs. I (R = F, R1 = R2 = SiMe2CMe3; R1 = SiMe2CMe3, R2 = H; R = Cl, Br, R1 = R2 = SiMe2CMe3) with lithium diisopropylamide (LDA) resulted in partial formation of the 1',2'-unsatd. 139878-41-4 and 784-71-4 are cas registry numbers of chemicals which are used as reagents here. nucleosides, with no lithiation being obsd. in the base moiety of the recovered starting material. Reactions of O2,2'-cyclouridine deriv. II with LDA or lithium 2,2,6,6-tetramethylpiperidide (LTMP) were also examd. The resulting product III was epoxidized to give nucleoside IV. The crystal structure of IV was detd. .

Enzymic preparation and antiviral activity of 2'-deoxy-2'-fluoro-ribavirin: Enzymic preparation and antiviral activity of 2'-deoxy-2'-fluoro-ribavirin. Slater, Martin J.; Gowrie, Clare; Freeman, G. A.; Short, S. A. (Glaxo Wellcome Medicines Research Centre, Stevenage SG1 2NY, UK).In this article, certain chemicals are used. Some of their cas registry numbers are 3641-08-5 and 784-71-4 Bioorganic & Medicinal Chemistry Letters, 6(22), 2787-2790 (English) 1996 Elsevier. CODEN: BMCLE8. ISSN: 0960-894X. DOCUMENT TYPE: Journal CA Section: 33 (Carbohydrates) Section cross-reference(s): 1, 7, 9 2'-Deoxy-2'-fluoro-ribavirin I has been efficiently synthesized from 2'-deoxy-2'-fluorouridine using nucleoside transferase as the key step, and evaluated for its antiviral properties in cell culture. An efficient synthesis of 3,5-di-O-p-chlorobenzoyl-2-deoxy-2-fluoro-b-D-ribofuranose is also described. I showed no activity against influenza A and B viruses up to 100mM in MDCK. None of the nucleosides showed any antiviral activity. .