Products Categories
| CAS No.: | 79-41-4 |
|---|---|
| Name: | 2-Methyl-2-propenoic acid |
| Article Data: | 290 |
| Molecular Structure: | |
|
|
|
| Formula: | C4H6O2 |
| Molecular Weight: | 86.0904 |
| Synonyms: | Methacrylicacid (8CI);2-Methyl-2-propenoic acid;2-Methylacrylic acid;Acryester MAA;GE110;Light Ester A;Loctite 3298;MAA;NSC 7393;NorsocrylMAA;a-Methacrylic acid;a-Methylacrylic acid;α-Methylacrylic acid; |
| EINECS: | 201-204-4 |
| Density: | 1.015 g/cm3 |
| Melting Point: | 16 °C |
| Boiling Point: | 160.499 °C at 760 mmHg |
| Flash Point: | 74.172 °C |
| Solubility: | 9.7 g/100 mL (20 °C) in water |
| Appearance: | colourless liquid or crystals with an unpleasant odour |
| Hazard Symbols: |
 C
|
| Risk Codes: | 21/22-35 |
| Safety: | 26-36/37/39-45 |
| Transport Information: | UN 2531 8/PG 2 |
| PSA: | 37.30000 |
| LogP: | 0.64710 |
- 81281-59-67-Benzylideneaminotheophylline
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 852475-26-4MC1568
- 958254-66-51H-Imidazo[4,5-b]pyridine-2-carboxaldehyde, 1-methyl-, hydrochloride
- 99170-93-1N-Methyl-2-oxazolamine
- 914458-26-7[5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-Methanone
- 894852-01-87-BROMO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
- 90221-55-92-bromo-5-methylbenzaldehyde
- 885590-99-82,3-DIFLUORO-4-IODOBENZALDEHYDE
- 97730-31-9(S)-4'-(2-Methylbutyl)Biphenyl-4-Carbonitrile
| Conditions | Yield |
|---|---|
| With potassium phosphate buffer at 30℃; for 16h; Rhodococcus sp. AJ270 cells; | 98% |
| With bradyrhizobium species BTAi1 (A5EKU8); water Reagent/catalyst; Enzymatic reaction; |
- 371-41-5
4-Fluorophenol
- 57-15-8
1,1,1-trichloro-2-methyl-2-propanol
A
- 79-41-4
poly(methacrylic acid)
B
- 587-11-1
2-(4-fluorophenoxy)-2-methylpropanoic acid
| Conditions | Yield |
|---|---|
| With sodium hydroxide In acetone for 16h; Ambient temperature; | A n/a B 88% |
| Conditions | Yield |
|---|---|
| Stage #1: 2-bromoprop-1-ene With magnesium In tetrahydrofuran at 20℃; for 0.5h; Stage #2: carbon dioxide In tetrahydrofuran at -70 - 20℃; under 750.075 Torr; Stage #3: With hydrogenchloride; ammonium chloride Product distribution / selectivity; more than 3 stages; | 87% |
| Stage #1: 2-bromoprop-1-ene; carbon dioxide With sodium hydroxide; tetrakis(triphenylphosphine) palladium(0); cetyltrimethylammonim bromide In water; toluene at 95℃; under 750.075 Torr; for 2h; Stage #2: With hydrogenchloride In water pH=< 7; Product distribution / selectivity; | 60% |
- 68430-08-0
2-(1-benzyl-4-methyl-1H-pyrazol-3-yloxy)-2-methyl-propionic acid
A
- 79-41-4
poly(methacrylic acid)
B
- 53409-18-0
1-benzyl-4-methyl-1,2-dihydro-pyrazol-3-one
| Conditions | Yield |
|---|---|
| at 150℃; for 5h; | A n/a B 85.1% |
- 68429-96-9
2-(1-benzyl-4-chloro-1H-pyrazol-3-yloxy)-2-methyl-propionic acid
A
- 79-41-4
poly(methacrylic acid)
| Conditions | Yield |
|---|---|
| Heating; | A n/a B 83.8% |
| Conditions | Yield |
|---|---|
| V-Si-P ternary oxide at 300℃; Product distribution; other temperatures; other contact times; other concentrations of the educts; or with water vapor; | A n/a B 82% |
| V-Si-P ternary oxide at 300℃; | A n/a B 82% |
| Conditions | Yield |
|---|---|
| sodium hydroxide In water at 300℃; under 262201 Torr; Product distribution / selectivity; | 80.8% |
- 62299-19-8
2-(1-Benzyl-1H-pyrazol-3-yloxy)-2-methyl-propionic acid
A
- 79-41-4
poly(methacrylic acid)
B
- 21074-40-8
1-benzyl-3-hydroxy-1H-pyrazole
| Conditions | Yield |
|---|---|
| Heating; | A n/a B 80.2% |
| Conditions | Yield |
|---|---|
| With oxygen; silica-alumina In water at 355℃; Product distribution / selectivity; | A 78.4% B 1.9% C 1.1% |
| With oxygen; silica-alumina In water at 355℃; Product distribution / selectivity; | A 78.1% B 2.2% C 1% |
| With oxygen; 5% Pd/zirconia In water at 130℃; under 36003.6 Torr; Product distribution / selectivity; autoclave; | |
| With oxygen; palladium on silica gel In water at 130℃; under 36003.6 Torr; Product distribution / selectivity; autoclave; |
- 67-66-3
chloroform
- 67-64-1
acetone
- 53409-18-0
1-benzyl-4-methyl-1,2-dihydro-pyrazol-3-one
A
- 79-41-4
poly(methacrylic acid)
B
- 594-61-6
2-methyllactic acid
C
- 594-58-1
2-chloro-2-methylpropanoic acid
D
- 68430-08-0
2-(1-benzyl-4-methyl-1H-pyrazol-3-yloxy)-2-methyl-propionic acid
| Conditions | Yield |
|---|---|
| With sodium hydroxide at 49 - 54℃; Further byproducts given; | A 0.07 mol B 0.15 mol C n/a D 77.2% |
- 107-92-6Butyric acid
- 539-86-6Allicin
- 4468-02-4Zinc gluconate
- 3734-33-6Denatonium benzoate
- 110-94-1Glutaric acid
- 7320-34-5Potassium pyrophosphate
- 83-86-3Phytic acid
- 108-55-42H-Pyran-2,6(3H)-dione,dihydro-
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
What can I do for you?
Get Best Price
Specification
The IUPAC name of Methacrylic acid is 2-methylprop-2-enoic acid. With the CAS registry number 79-41-4, it is also named as 2-Methylenepropionic acid. The classification codes are Drug / Therapeutic Agent and Mutation data. It is colourless liquid or crystals with an unpleasant odour which is soluble in warm water and miscible with most organic solvents. Methacrylic acid is corrosive to metals and tissue and may polymerize exothermically if heated or contaminated. If the polymerization takes place inside a container, the container may rupture violently. It is flammable, so people should keep it away from oxidants and bases. Additioanlly, this chemical should be sealed in the container and stored in the cool, ventilate and dry place.
The other characteristics of this product can be summarized as: (1)ACD/LogP: 0.57; (2)# of Rule of 5 Violations: 0; (3)ACD/BCF (pH 5.5): 1; (4)ACD/BCF (pH 7.4): 1; (5)ACD/KOC (pH 5.5): 5.265; (6)ACD/KOC (pH 7.4): 1; (7)#H bond acceptors: 2; (8)#H bond donors: 1; (9)#Freely Rotating Bonds: 1; (10)Index of Refraction: 1.43; (11)Molar Refractivity: 21.713 cm3; (12)Molar Volume: 84.083 cm3; (13)Polarizability: 8.608×10-24 cm3; (14)Surface Tension: 30.92 dyne/cm; (15)Enthalpy of Vaporization: 43.796 kJ/mol; (16)Vapour Pressure: 1.232 mmHg at 25 °C; (17)Rotatable Bond Count: 1; (18)Exact Mass: 86.036779; (19)MonoIsotopic Mass: 86.036779; (20)Topological Polar Surface Area: 37.3; (21)Heavy Atom Count: 6; (22)Complexity: 83.5.
Preparation of Methacrylic acid: It can be obtained by the two-step oxidation of isobutylene. First oxidation to get methacrolein and second oxidation to get methacrylic acid. And then we can get qualified products by distillation.
CH2=C(CH3)CH3+O2→CH2=C(CH3)CHO+H2O
CH2=C(CH3)CHO+ 1/2O2→CH2=C(CH3)COOH
Uses of Methacrylic acid: It is used in the manufacture of paints, insulation materials, adhesives, and ion exchange resins. It is also used as important organic chemical raw material and polymer intermediate. Methacrylic acid is organic reagent. In addition, it can react with oxirane to get methacrylic acid-(2-hydroxy-ethyl ester). This reaction needs reagents water and triethylamine at temperature of 125 °C.
.gif)
When you are using this chemical, please be cautious about it as the following:
It is harmful by inhalation and in contact with skin. And it also can cause severe burns. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
People can use the following data to convert to the molecule structure.
(1)SMILES: CC(=C)C(=O)O
(2)InChI: InChI=1/C4H6O2/c1-3(2)4(5)6/h1H2,2H3,(H,5,6)(3)InChIKey: CERQOIWHTDAKMF-UHFFFAOYAE
The following are the toxicity data which has been tested.
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| child | TDLo | oral | 250uL/kg (0.25mL/kg) | LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI GASTROINTESTINAL: NAUSEA OR VOMITING SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | Pediatrics. Vol. 102, Pg. 979, 1998. |
| dog | LDLo | intravenous | 95200nL/kg (95200mL/kg) | Journal of Pharmaceutical Sciences. Vol. 63, Pg. 376, 1974. | |
| guinea pig | LD50 | skin | 1gm/kg (1000mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4953, 1982. | |
| mouse | LD50 | intraperitoneal | 48mg/kg (48mg/kg) | Journal of Pharmaceutical Sciences. Vol. 62, Pg. 778, 1973. | |
| mouse | LD50 | oral | 1250mg/kg (1250mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(11), Pg. 57, 1981. | |
| mouse | LD50 | unreported | 1250mg/kg (1250mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(10), Pg. 64, 1984. | |
| rabbit | LD50 | oral | 1200mg/kg (1200mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 38(8), Pg. 13, 1973. | |
| rabbit | LD50 | skin | 500mg/kg (500mg/kg) | "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986Vol. 5, Pg. 362, 1986. | |
| rat | LD50 | oral | 1060mg/kg (1060mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 41(4), Pg. 6, 1976. | |
| rat | LD50 | unreported | 1600mg/kg (1600mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(10), Pg. 64, 1984 |