Detail of "791-35-5"

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Isolation and identification of some Clofedanol metabolites from human urine: Isolation and identification of some Clofedanol metabolites from human urine. Eckhardt, G.; Goenechea, S.; Tondorf, G. (Inst. Org. Chem. Biochem., Univ. Bonn, Bonn, Ger.). J. Clin. Chem. Clin. Biochem., 15(12), 687-90 (German) 1977. CODEN: JCCBDT. ISSN: 0340-076X. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Ten metabolites of Clofedanol (I) [791-35-5] were identified in human urine. The following 5 products were extd. with CHCl3 at pH 1-2: o-(chlorophenyl)phenylmethane [29921-41-3], benzophenone [119-61-9], o-chlorobenzophenone [5162-03-8], benzhydrol [91-01-0], and o-(chlorophenyl)-b-phenylacrolein [66171-83-3]. Two compds. were extd. with CHCl3 at pH 13-14: unchanged I and 1-(o-chlorophenyl)-1-phenyl-3-dimethylamino-1-propene [66171-84-4]. N,N-dimethylamino-acetic acid [1118-68-9] was also identified in urine. I and benzhydrol were present as free compds., and they were also found after hydrolysis of their resp. glucuronides with b-glucuronidase.

High performance liquid chromatographic determination of chlophedianol hydrochloride in "Jung Fei", a complex tablet formulation: High performance liquid chromatographic determination of chlophedianol hydrochloride in "Jung Fei", a complex tablet formulation. Burrows, Gregory W.; Evertts, Victoria L. (Anal. Chem. Dep., Food and Drug Res. Lab., Inc., Waverly, NY 14892, USA). J. Chromatogr. Sci., 23(1), 37-8 (English) 1985. CODEN: JCHSBZ. ISSN: 0021-9665. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) A HPLC method is presented for the detn. of chlophedianol (I) [791-35-5] as the I-HCl in a complex tablet formulation. Tablets are dissolved in a H2O-MeCN () mixt. Samples are sepd. on an octadecylsilane column with a mobile phase of 70% MeCN and 30% aq. soln. of 0.005M 1-octanesulfonic acid, 1% HOAc, and 1% diethylamine. Effluent is monitored by a spectrophotometric detector with a 254-nm filter. I is sepd. from a complex mixt. of plant exts. and fillers in the tablets.