Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products > 8001 > 

8001-35-2

Products Categories

Basic Information
CAS No.: 8001-35-2
Name: Toxaphene
Article Data: 3
Molecular Structure:
Molecular Structure of 8001-35-2 (Toxaphene)
Formula: C10H15Cl
Molecular Weight: 170.6791
Synonyms: Alltox;Anatox; Camphechlor; Camphochlor; Canfeclor; Chlorinated camphene; Estonox;Geniphene; Hercules 3956; Kamfochlor; M 5055; Melipax; PCC; PChK; PChK(insecticide); PKhF; Phenacide; Phenatox; Polychlorocamphene; Strobane T;Toxakil; Toxaphen; Toxyphen
EINECS: 232-283-3
Density: 1.6
Melting Point: 65 - 90 C
Boiling Point: (decomposes)
Flash Point: 4°C
Solubility: negligible
Appearance: yellow waxy solid
Hazard Symbols: Toxic by ingestion, inhalation, skin absorption; most uses prohibited. TLV: 0.5 mg/m3; STEL 1 mg/m3); animal carcinogen.
Risk Codes: 21-25-37/38-40-50/53-67-65-38-11-36/37/38-39/23/24/25-23/24/25
Safety: Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Human poison by ingestion and possibly other routes. Experimental poison by ingestion, intraperitoneal, and possibly other routes. Moderately toxic experimentally by inhalation and skin contact. Human systemic effects by ingestion and skin contact: somnolence, convulsions or effect on seizure threshold, coma, and allergic skin dermatitis. A skin irritant; absorbed through the skin. Experimental teratogenic and reproductive effects. Human mutation data reported. Liver injury has been reported. Lethal amounts of toxaphene can enter the body through the mouth, lungs, and skin. Systemic absorption of the insecticide is increased by the presence of digestible oils, and liquid preparations of the insecticide, which penetrate the skin more readily than do dusts and wettable powders.

A toxic mixture of organochlorine pesticides stored to some extent in body fat. It resembles chlordane and, to some extent, camphor in its physiological action. It causes diffuse stimulation of the brain and spinal cord resulting in generalized convulsions of a tonic or clonic character. Death usually results from respiratory failure. Detoxification appears to occur in the liver. The lethal ingestion dose for humans is estimated to be 2–7 g, a toxicity of about four times that of DDT. At least seven human deaths have been reported due to toxaphene, all in children. Two families have been made ill by eating vegetables containing a large residue of toxaphene. When heated to decomposition it emits toxic fumes of Cl.

Analytical Methods:

   

For occupational chemical analysis use NIOSH: Chlorinated Camphene S67.

PSA: 0.00000
LogP: 6.62720
  • Display:default sort

    New supplier

  • Total:0 Page 0 of 0
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 8001-35-2

Chemistry

IUPAC Name:1,2,3,4,7,7-hexachloro-6,6-bis(chloromethyl)-5-methylidenebicyclo[2.2.1]heptane
Molecular Formula:C10H10Cl8
Molecular Weight:413.80
Melting Point:65 - 90°C
Water Solubility:Negligible
Storage temp.:2-8°C
Merck:13,9633
Appearance:Yellow waxy solid
CHLORINATED CAMPHENE's(8001-35-2) Synonyms: ALLTEX(R);CAMPHECHLOR;CAMPHECHLOR-(TOXAPHENE);GENIPHENE(R);HERCULES 3956(R);CHLORINATED CAMPHENE;POLYCHLOROBICYCLIC TERPENES;PHENETOX(R)   
CHLORINATED CAMPHENE's(8001-35-2) Molecular Structure:

Toxicity Data With Reference

1.   

skn-mam 500 mg MOD

   JAMAAP    JAMA, Journal of the American Medical Association. 149 (1952),1135.
2.   

mmo-sat 100 µg/plate

   ENMUDM    Environmental Mutagenesis. 8 (Suppl 7)(1986),1.
3.   

mma-sat 500 µg/plate

   SCIEAS    Science. 205 (1979),591.
4.   

sce-hmn:lym 10 µmol/L

   ARTODN    Archives of Toxicology. 52 (1983),221.
5.   

otr-mus:emb 12,400 µg/L

   PMRSDJ    Progress in Mutation Research. 5 (1985),659.
6.   

orl-hmn LDLo:28 mg/kg:CNS

   34ZIAG    Toxicology of Drugs and Chemicals, Deichmann, W.B.,New York, NY.: Academic Press, Inc.,1969,598.
7.   

orl-man LDLo:29 mg/kg

   CMEP**    Clinical Memoranda on Economic Poisons US Dept. HEW, Public Health Service, Communicable Disease Center,Atlanta, GA.: 1956,1.
8.   

skn-hmn TDLo:657 mg/kg:SKN

   CMEP**    Clinical Memoranda on Economic Poisons US Dept. HEW, Public Health Service, Communicable Disease Center,Atlanta, GA.: 1956,1.
9.   

unr-man LDLo:44 mg/kg

   85DCAI    Poisoning; Toxicology, Symptoms, Treatments. 2 (1970),73.
10.   

orl-rat LD50:50 mg/kg

  &

Consensus Reports

NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 20 , 1979,p. 327.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 20 , 1979,p. 327.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (feed); Clear Evidence: mouse, rat NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-37 ,1979. . EPA Extremely Hazardous Substances List.

Safety Profile

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Human poison by ingestion and possibly other routes. Experimental poison by ingestion, intraperitoneal, and possibly other routes. Moderately toxic experimentally by inhalation and skin contact. Human systemic effects by ingestion and skin contact: somnolence, convulsions or effect on seizure threshold, coma, and allergic skin dermatitis. A skin irritant; absorbed through the skin. Experimental teratogenic and reproductive effects. Human mutation data reported. Liver injury has been reported. Lethal amounts of toxaphene can enter the body through the mouth, lungs, and skin. Systemic absorption of the insecticide is increased by the presence of digestible oils, and liquid preparations of the insecticide, which penetrate the skin more readily than do dusts and wettable powders.

A toxic mixture of organochlorine pesticides stored to some extent in body fat. It resembles chlordane and, to some extent, camphor in its physiological action. It causes diffuse stimulation of the brain and spinal cord resulting in generalized convulsions of a tonic or clonic character. Death usually results from respiratory failure. Detoxification appears to occur in the liver. The lethal ingestion dose for humans is estimated to be 2–7 g, a toxicity of about four times that of DDT. At least seven human deaths have been reported due to toxaphene, all in children. Two families have been made ill by eating vegetables containing a large residue of toxaphene. When heated to decomposition it emits toxic fumes of Cl.

Safety Information of CHLORINATED CAMPHENE(8001-35-2)
Hazard Codes  T,N,Xn,F,Xi
Risk Statements  21-25-37/38-40-50/53-67-65-38-11-36/37/38-39/23/24/25-23/24/25
Safety Statements  36/37-45-60-61-62-33-16-36-26
RIDADR  2761
RTECS  XW5250000
HazardClass  6.1(b)
PackingGroup  III

Standards and Recommendations

OSHA PEL: TWA 0.5 mg/m3; STEL 1 mg/m3 (skin)
ACGIH TLV: TWA 0.5 mg/m3; STEL 1 mg/m3 (skin); Animal Carcinogen
DFG MAK: Animal Carcinogen, Suspected Human Carcinogen

Analytical Methods

For occupational chemical analysis use NIOSH: Chlorinated Camphene S67.