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Detail of "8003-03-0"

  • CAS Number:
  • 8003-03-0
  • Name:
  • ASPIRIN, PHENACETIN, and CAFFEINE

  • Formula:
  • C10H13NO2•C9H8O4•C8H10N4O2
  • Molecular Weight:
  • 553.63
  • Synonyms:
  • MIXTUREOFASPIRIN,PHENACETINANDCAFFEINE
  • Solubility:
  • negligible Stability Stable. Incompatible with strong oxidizing agents. Toxicology Harmful if taken over an extended period of time, orif ingested in large amounts. Phenacetin is a suspected carcinogen.
  • Appearance:
  • white powder
  • Safety:
  • Moderately toxic by ingestion. Questionable carcinogen with experimental tumorigenic data. See also CAFFEINE, p-ACETOPHENETIDIDE. When heated to decomposition it emits toxic fumes of NOx. Details

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CAS No.8003-03-0 ASPIRIN, PHENACETIN, and CAFFEINE

  Appearance:Slightly bit...

mp 134-135° One gram dissolves in 1310 ml cold water, 82 ml boiling water; 15 ml cold alcohol, 2.8 ml boiling alcohol; 14 ml chloroform, 90 ml ether; sol in glycerol. Gives a pasty mass with phenol, chloral hydrate or pyrocatechol, strong acids or alkalies, salicylic acid, oxidiz

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Reference

Antidiarrheal constituents of burned substances of compound acetylsalicylic acid tables
Antidiarrheal constituents of burned substances of compound acetylsalicylic acid tables. Li, Yaqing; Zhang, Xiaoyou; Zhou, Bentian; Liu, Baili; Wang, Xiu; Zhuang, Dianyou; Zhou, Yanmin; Liu, Li (Daqing First Hosp., Daqing, Peop. Rep. China). Shenyang Yaoxueyuan Xuebao, 3(4), 264-7 (Chinese) 1986. CODEN: SYXUE3. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Aspirin [50-78-2], phenacetin [62-44-2], salicylic acid [69-72-7], Et salicylate [118-61-6], Ph salicylate [118-55-8] and efuamide [N-(4-ethoxyphenyl)-2-hydroxybenzamide](I) [64700-55-6] were identified in the burned ash of APC [8003-03-0] tablets. Aspirin and Ph salicylate inhibited peristalsis in the rat stomach and intestine and I had strong immunosuppressant activity in pharmacol. 62-44-2 and 69-72-7 which are cas registry numbers of substances are two of reagents here. tests. .
Application of thin-layer chromatography to the quantitative analysis of analgesic mixture
Application of thin-layer chromatography to the quantitative analysis of analgesic mixture. Cadorniga, R.; Camacho, M. A.; Dominguez-Gil, A. (Fac. Farm., Univ. Complutense Madrid, Madrid, Spain). Cienc. Ind. Farm., 9(4), 88-91 (Spanish) 1977. CODEN: CIDFA8. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) In a thin-layer chromatog. study using 11 solvent systems for the sepn. of a acetylsalicylic acid-caffeine-phenacetin mixt. (I-II-III mixt.) [8003-03-0], best results were obtained with a benzene-Me2CO or a : BuOAc-Me2CO-BuOH-NH4OH system.
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