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| CAS No.: | 8014-29-7 |
|---|---|
| Name: | RUE OIL |
| Molecular Structure: | |
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| Formula: | N/A |
| Molecular Weight: | 0 |
| Synonyms: | Oil of Rue;Rue oil |
| Density: | 0.832-0.845 |
| Safety: | Moderately toxic by ingestion. A skin irritant. Frequent skin contact causes erythema, vesication. Ingestion of large quantities produces epigastric pain, nausea, vomiting, confusion, convulsions, death; may terminate pregnancy. When heated to decomposition it emits acrid smoke and irritating fumes. |
| PSA: | 0.00000 |
| LogP: | 0.00000 |
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Chemistry
Product Name: Rue oil
Synonyms: Oilofrue ; Oils,rue ; Rue essence oliffac ; Rue oil ; Fema 2994 ; Ruta graveolens (rue) oil ; Rue ; Rlle oil
CAS NO: 8014-29-7
Classification Code: Natural Product ; Skin / Eye Irritant ; TSCA UVCB
History
Origin of rue oil
A native of Europe, it is an ornamental, shrubby herb with a strong, aromatic, bitter or acrid scent and has tough, woody branches and small, smooth, bluish-green leaves. Mustard-yellow, fringed 4-petalled flowers appear in summer, followed by 4-lobed capsules.
In ancient medicine, the herb was a favored remedy as an antidote to poison and was seen as a magic herb by many cultures and as a protection against evil. It was used for nervous afflictions, digestive problems and hysterics.
Rue essential oil is considered toxic, an abortifacient, an irritant to the mucus membranes, a neurotoxin, and causes sun sensitivity due to photo toxicity.
Uses
Oil of rue (CAS NO.8014-29-7) have been used to treat eyestrain, sore eyes, and as an insect repellent.
Production
Raw materials: RUTA GRAVEOLENS
Oil of rue (CAS NO.8014-29-7) is extracted from the fresh herb by steam distillation.
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | oral | 2070mg/kg (2070mg/kg) | Food and Cosmetics Toxicology. Vol. 13, Pg. 455, 1975. | |
| rabbit | LD50 | skin | > 5gm/kg (5000mg/kg) | Food and Cosmetics Toxicology. Vol. 13, Pg. 455, 1975. | |
| rat | LD50 | oral | > 5gm/kg (5000mg/kg) | Food and Cosmetics Toxicology. Vol. 13, Pg. 455, 1975. |
Consensus Reports
Reported in EPA TSCA Inventory.
Safety Profile
Moderately toxic by ingestion. A skin irritant. Frequent skin contact causes erythema, vesication. Ingestion of large quantities produces epigastric pain, nausea, vomiting, confusion, convulsions, death; may terminate pregnancy. When heated to decomposition it emits acrid smoke and irritating fumes.
FEMA: 2994
Specification
Oil of rue (CAS NO.8014-29-7) should not be used in aromatherapy as it is a hazardous oil that can burn and irritate the skin.