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8057-51-0

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Basic Information
CAS No.: 8057-51-0
Name: CRATAEGUS MONOGINA FRUIT EXTRACT
Molecular Structure:
Molecular Structure of 8057-51-0 (CRATAEGUS MONOGINA FRUIT EXTRACT)
Formula: N/A
Molecular Weight: 0
Synonyms: CRATAEGUS MONOGINA FRUIT EXTRACT;Hawthorn, ext.
Safety: Poison by intravenous route. Mildly toxic by ingestion.
PSA: 0.00000
LogP: 0.00000
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Chemistry

Product Name: Esbericard 
Synonyms of Esbericard (CAS NO.1448-23-3) : UNII-WY4PQ9PE1Q ; Crataegus, extract
Classification Code :Natural Product
CAS NO:1448-23-3
Molecular Structure:Unspecified

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intravenous 1200mg/kg (1200mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Planta Medica. Vol. 43, Pg. 105, 1981.
duck LDLo intravenous 300mg/kg (300mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Planta Medica. Vol. 43, Pg. 105, 1981.
frog LDLo parenteral 5gm/kg (5000mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Planta Medica. Vol. 43, Pg. 105, 1981.
guinea pig LDLo intravenous 1500mg/kg (1500mg/kg) CARDIAC: CHANGE IN RATE

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Planta Medica. Vol. 43, Pg. 105, 1981.
mouse LD50 oral 18500mg/kg (18500mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)		 Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 16, Pg. 68, 1969.
rabbit LDLo intravenous 1gm/kg (1000mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Planta Medica. Vol. 43, Pg. 105, 1981.
rat LD50 oral 33800mg/kg (33800mg/kg)   Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 16, Pg. 68, 1969.
rat LDLo intravenous 1gm/kg (1000mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Planta Medica. Vol. 43, Pg. 105, 1981.

Safety Profile

Poison by intravenous route. Esbericard (CAS NO.1448-23-3) is mildly toxic by ingestion.