Reference

Effect of alkoxy groups on the stability of cations in the gas phase

Effect of alkoxy groups on the stability of cations in the gas phase. Ponomarev, D. A.; Takhistov, V. V.; Tamash, I.; Tsira, G. (Leningr. Gos. Univ. im.Some commonly used reagents like 824-98-6 and 824-94-2 are used in this experiment. Zhdanova, Leningrad, USSR). Izv. Vyssh. Uchebn. Zaved., Khim. Khim. Tekhnol., 20(1), 136-7 (Russian) 1977. CODEN: IVUKAR. DOCUMENT TYPE: Journal CA Section: 22 (Physical Organic Chemistry) For RC6H4CH2Cl (R = m-MeO, p-MeO, m-Me3CO, p-Me3CO) the ionization potentials and appearance potentials of the [M-Cl]+ ion were as follows: 8.1, 9.7; 8.1, 8.7; 7.9, 10.6; 8.2, 9.4 eV. The absence of a Baker-Nathan effect was ascribed to steric interaction between the ring and the alkoxy group. .

Preparation of fused 3-hydroxypyrimidine-2,4-diones as inhibitors of flap endonuclease

Preparation of fused 3-hydroxypyrimidine-2,4-diones as inhibitors of flap endonuclease. Tumey, Lawrence N.; Bennani, Youssef; Huck, Bayard; Bom, David C. ( Athersys, Inc., USA). PCT Int. Appl. WO 2006014647 A2 9 Feb 2006, 65 pp. DESIGNATED STATES: W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW; RW: AT, BE, BF, BJ, CF, CG, CH, CI, CM, CY, DE, DK, ES, FI, FR, GA, GB, GR, IE, IS, IT, LU, MC, ML, MR, NE, NL, PT, SE, SN, TD, TG, TR. (English). (World Intellectual Property Organization). CODEN: PIXXD2. APPLICATION: WO 2005-US25592 20 Jul 2005. PRIORITY: US 2004-2004/PV589635 21 Jul 2004.In this article, certain chemicals are used. One of their cas registry numbers is 824-98-6 DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1, 7, 63 Title compds. I (X , Y = C, O, S provided one of X and Y = C; when X = C, R1 is present and selected from group consisting of H, aryl, heteroaryl, alkyl, alkylaryl, fused aryl with R2, fused cycloalkyl with R2; R2 = H, aryl, heteroaryl, alkyl, alkylaryl, fused aryl with R1 or R3, fused cycloalkyl with R1 or R3; when Y = C, R3 is present and selected from group consisting of H, aryl, heteroaryl, alkyl, alkylaryl, fused aryl with R2, fused cycloalkyl with R2; R4 = alkyl, aryl, heteroaryl, alkylaryl) were prepd., including their pharmaceutically acceptable salts and isomers, for use in pharmaceutical compns. as inhibitors of flap endonuclease (biol. activity data not given). For example, 2-aminothiophene-3-carboxylic acid Et ester was refluxed in toluene along with carbonyl diimidazole, followed by addn. of O-(2,4-dimethoxybenzyl)hydroxylamine to afford the cyclized product II. 155807-64-0 is also in the experiment. Deprotection of II led to final product I (X = C, Y = S, R1 = R2 = R4 = H, R3 = not present). ..