Detail of "82570-80-7"

Reference

Quinolizidines

Quinolizidines. XVI. Chiral syntheses of 9-demethylcephaeline and 10-demethylcephaeline. Fujii, Tozo; Ohba, Masashi (Fac. Pharm. Sci.Several reagents such as 82570-80-7 is used here., Kanazawa Univ., Kanazawa 920, Japan). Chem. Pharm. Bull., 33(12), 5264-9 (English) 1985.Several substances with their cas registry numbers 82514-00-9 and 36455-21-7 may be metioned in this study. CODEN: CPBTAL. ISSN: 0009-2363. DOCUMENT TYPE: Journal CA Section: 31 (Alkaloids) In order to establish the structure of the Alangium alkaloid demethylcephaeline, chiral syntheses of the two possible alternative structures, (-)-9-demethylcephaeline (I, R = H, R1 = Me) and (-)-10-demethylcephaeline (I, R = Me, R1 = H) were accomplished through a cincholoipon-incorporating route. The synthesis of (-)-I (R = Me, R1 = H) started with an initial condensation of the tricyclic acid (-)-II with 3-benzyloxy-4-methoxyphenethylamine and proceeded through the intermediates III and IV. The 1'-epimers were also produced in this reaction sequence. (-)-I (R = H, R1 = Me) was prepd by a parallel sequence. Unfortunately, however, lack of a sufficient amt. of natural (-)-demethylcephaeline for a detailed and direct comparison precluded identification of either I with this alkaloid, leaving its chem. incomplete. ..