Detail of "827-43-0"

Reference

Carbene reactions with benzonitrile oxides

Carbene reactions with benzonitrile oxides. Note II. Synthesis and transformation of 1,3-oxazin-6-ones into imidazoles. Lo Vecchio, G.; Grassi, G.; Risitano, F.; Foti, F.; Caruso, F. (Fac. Sci., Univ. Messina, Messina, Italy). Chim. Ind. (Milan), 58(6), 451 (Italian) 1976. CODEN: CINMAB. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Reaction of the isoxazolone autocondensation product I with PhCNO gave the imidazole II (R = 3-methyl-5-isoxazolyl, III) via an oxazinone intermediate. Hydrogenation of III gave II (R = COCH2CMe:NH), which condensed with PhNHNH2 to give II (R = 3-methyl-1-phenyl-5-pyrazolyl). 873-67-6 and 827-43-0 are just another two chemicals used in this study. Treatment of II (R = COCH2CMe:NH) with KOH gave II (R = Ac), which was oxidized to II (R = CO2H) and decarboxylated. .

Imidazole derivatives

Imidazole derivatives. Schunack, Walter; Wegner, Kurt (Heumann, Ludwig, und Co. G.m.b.H., Ger.). Ger. Offen. DE 2533211 10 Feb 1977, 14 pp. (German). (Germany). CODEN: GWXXBX.Several substances with their cas registry numbers 100-54-9 and 827-43-0 may be metioned in this study. CLASS: IC: C07D233-58. APPLICATION: DE 75-2533211 24 Jul 1975. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Imidazoles (I; R = H, Me, cyclohexyl; R1 = Me, Ph, cyclohexyl, 4-MeOC6H4, 4-ClC6H4CH2, 3-pyridinyl; R2 = Me, Et, Pr, PhCH2, MeSCH2CH2; R3 = H, Me, Et, Pr, PhCH2, Me2CHCH2, MeSCH2CH2) are prepd. by reaction of an imidate or amidine with an .alpha.-(acylamino) ketone and NH3 under pressure. Thus, reaction of PhC(:NH)OEt.HCl with AcNHCH2COMe and NH3 at 80.degree./35 atm gives after 15 h I (R = R3 = H, R1 = Ph, R2 = Me). .