Detail of "83354-70-5"
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- Glycoslyated derivatives of benzophenone, benzhydrol and benzhydril as potential venous antithrombotic agents
- Glycoslyated derivatives of benzophenone, benzhydrol and benzhydril as potential venous antithrombotic agents. Bellamy, Francois; Horton, Derek; Millet, Jean; Picart, Francois; Samreth, Soth; Chazan, Jean Bernard (Cent. Res., Lab. Fournier S.A., Daix 21121, Fr.). J. 83354-70-5 is just another one chemical used in this study. Med. Chem., 36(7), 898-903 (English) 1993. CODEN: JMCMAR. ISSN: 0022-2623. DOCUMENT TYPE: Journal CA Section: 33 (Carbohydrates) Section cross-reference(s): 1 A series of glycosylated derivs. of benzophenone, benzhydrol, and benzhydril has been synthesized and evaluated for potential activity as venous antithrombotic agents. Studies on structure-activity relationships revealed that compds. having an electron-withdrawing group in the benzhydril or benzhydrol moiety, and specifically those having the b-D-xylopyranosyl structure in the sugar moiety, were good antithrombotic agents in a rat model of venous thrombosis. .


