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Basic Information
| CAS No.: | 84-04-8 |
|---|---|
| Name: | pipamazine |
| Article Data: | 3 |
| Molecular Structure: | |
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| Formula: | C21H24 Cl N3 O S |
| Molecular Weight: | 401.96 |
| Synonyms: | Isonipecotamide,1-[3-(2-chlorophenothiazin-10-yl)propyl]- (6CI,7CI,8CI); 1-[3-(2-Chlorophenothiazin-10-yl)propyl]isonipecotamide;10-[3-(4-Carbamoylpiperidino)propyl]-2-chlorophenothiazine; Mornidine;Nausidol; Nometine; Pipamazine; RP 9153; SC 9387 |
| Density: | 1.277g/cm3 |
| Melting Point: | about 139° |
| Boiling Point: | 626.6°C at 760 mmHg |
| Flash Point: | 332.8°C |
| Safety: | Poison by ingestion and intraperitoneal routes. Human (child) systemic effects by ingestion: somnolence, sleep, and coma. When heated to decomposition it emits very toxic fumes of SOx, NOx, and Cl−. |
| PSA: | 75.86000 |
| LogP: | 5.68270 |
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pipamazine
Toxicity Data With Reference
| 1. | orl-chd TDLo:500 µg/kg:CNS | 34ZIAG Toxicology of Drugs and Chemicals ,Deichmann, W.B.,New York, NY.: Academic Press, Inc.,1969,478. | ||
| 2. | orl-rat LD50:620 mg/kg | 27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,39. | ||
| 3. | orl-mus LD50:370 mg/kg | 27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,39. | ||
| 4. | ipr-mus LD50:80 mg/kg | 27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,39. |
Safety Profile
Poison by ingestion and intraperitoneal routes. Human (child) systemic effects by ingestion: somnolence, sleep, and coma. When heated to decomposition it emits very toxic fumes of SOx, NOx, and Cl−.